PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells

SM Kim, TT Nguyen, A Ravi, P Kubiniok, BT Finicle… - Cancer discovery, 2018 - AACR
We report that PTEN-deficient prostate cancer cells use macropinocytosis to survive and
proliferate under nutrient stress. PTEN loss increased macropinocytosis only in the context …

An organoid assay for long-term maintenance and propagation of mouse prostate luminal epithelial progenitors and cancer cells

Y Shu, CW Chua - Mouse Cell Culture: Methods and Protocols, 2019 - Springer
Historically, prostate luminal epithelial progenitors and cancer cells have been difficult to
culture, thus hampering the generation of representative models for the study of prostate …

[PDF][PDF] Compartmentalized Hydrogel Microcapsules and Their Applications in Microtissue Engineering

YC Lu - 2018 - ecommons.cornell.edu
Three-dimensional (3D) cell culture has been broadly used to mimic the in-vivo
microenvironment. Compared with traditional methods for 3D culture in which cells are …

[BOOK][B] The Contribution of Sox2+ Cells to Prostate Epithelium Development, Regeneration, and Hyperplasia

EM McAuley - 2018 - search.proquest.com
Despite intensive study, gaps remain in our understanding of prostate epithelial stem cell
specification and resulting lineage relationships. Identification of defined epithelial cell …