Automated Image-Based Fluorescence Screening of Mitochondrial Membrane Potential in Daphnia magna: An Advanced Ecotoxicological Testing Tool

C Abele, A Perez, A Höglund… - Environmental …, 2024 - ACS Publications
This study demonstrated the strengths of in vivo molecular staining coupled with automated
imaging analysis in Daphnia magna. A multiwell plate protocol was developed to assess …

Investigating the Anticancer Potential of Biochanin A in KB Oral Cancer Cells Through the NFκB Pathway

J Nivedha, L Vennila, G Sindhu… - Cell Biochemistry …, 2024 - Wiley Online Library
Squamous cell carcinoma (SCC) is a malignancy primarily affecting squamous cells. Its
development is linked to multiple risk factors, such as alcohol and tobacco consumption …

[HTML][HTML] Rotenone induced neurodegeneration is mediated via cytoskeleton degradation and necroptosis

T Roy, A Chatterjee, S Swarnakar - Biochimica et Biophysica Acta (BBA) …, 2023 - Elsevier
Rotenone has widespread beneficial effects in agriculture, fisheries and animal
husbandries; however prolonged exposure causes a detrimental effect on the health of …

Unveiling the cytotoxicity of phytosynthesised silver nanoparticles using Tinospora cordifolia leaves against human lung adenocarcinoma A549 cell line

J Mittal, U Pal, L Sharma, AK Verma… - IET …, 2020 - Wiley Online Library
Biosynthesis of silver nanoparticles (AgNPs) using plant extract is a cheap, easily accessible
and natural process in which the phyto‐constituents of the plants act as cap**, stabilising …

[HTML][HTML] dl-Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation: a potential non-surfactant spermicide for contraception

M **a, M Yang, Y Wang, F Tian, J Hu, W Yang… - Biomedicine & …, 2020 - Elsevier
Abstract dl-Mandelic acid (MA), an alpha-hydroxycarboxylic acid, has been widely used as
an intermediate of pharmaceutical and fine chemicals. Here, we evaluated the sperm …

[HTML][HTML] Diclofenac and atrazine restrict the growth of a synchronous Chlamydomonas reinhardtii population via various mechanisms

D Harshkova, M Majewska, W Pokora… - Aquatic Toxicology, 2021 - Elsevier
Non-steroidal anti-inflammatory drug diclofenac (DCF) is commonly found in freshwater
bodies and can have adverse effects on non-target organisms. Among the studies on DCF …

Effects of tritium pollution on photosynthesis, respiration and redox of microalgae under rising temperature

J Luo, Y Huang, J Lai, J Liang, X Luo, C Li… - Science of The Total …, 2025 - Elsevier
Due to rising sea surface temperatures and thermal emissions from nuclear power plants,
temperature has been recognized as a significant factor in evaluating the potential biological …

Mitochondria dysfunction is one of the causes of diclofenac toxicity in the green alga Chlamydomonas reinhardtii

D Harshkova, E Zielińska, M Narajczyk, M Kapusta… - PeerJ, 2024 - peerj.com
Background Non-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac (DCF),
form a significant group of environmental contaminants. When the toxic effects of DCF on …

[HTML][HTML] Interrogation on the cellular nano-interface and biosafety of repeated nano-electroporation by nanostraw system

A Zhang, J Fang, J Wang, X **e, HJ Chen, G He - Biosensors, 2022 - mdpi.com
Cell perforation is a critical step for intracellular drug delivery and real-time biosensing of
intracellular signals. In recent years, the nanostraws system has been developed to achieve …

[HTML][HTML] Diclofenac Interacts with Photosynthetic Apparatus: Isolated Spinach Chloroplasts and Thylakoids as a Model System

M Majewska, M Kapusta, A Aksmann - Plants, 2024 - mdpi.com
Diclofenac, often detected in environmental samples, poses a potential hazard to the aquatic
environment. The present study aimed to understand the effect of this drug on photosynthetic …