In recent years, there has been increasing interest in using biomimetic materials for bone
tissue engineering. However, the high immunogenicity and low mechanical properties of …

Polymer-based nanocapsules have been widely studied as a potential drug delivery system
in recent years. Nanocapsules—as one of kind nanoparticle—provide a unique …

Biodegradable polymers have met with an increasing demand in medical usage over the
last decades. One of such polymers is poly (ε-caprolactone)(PCL), which is a polyester that …

Bone tissue has a remarkable ability to regenerate and heal itself. However, large bone
defects and complex fractures still present a significant challenge to the medical community …

Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …

The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

The controlled delivery of growth factors and cells within biomaterial carriers can enhance
and accelerate functional bone formation. The carrier system can be designed with pre …

Bone vasculature plays a vital role in bone development, remodeling and homeostasis. New
blood vessel formation is crucial during both primary bone development as well as fracture …