Advances in mass spectrometry imaging for spatial cancer metabolomics
X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …
analyze various types of biomolecules in complex biological matrices makes it well suited for …
[HTML][HTML] Monitoring and modelling the dynamics of the cellular glycolysis pathway: A review and future perspectives
Background The dynamics of the cellular glycolysis pathway underpin cellular function and
dysfunction, and therefore ultimately health, disease, diagnostic and therapeutic strategies …
dysfunction, and therefore ultimately health, disease, diagnostic and therapeutic strategies …
A guide to MALDI imaging mass spectrometry for tissues
JL Moore, G Charkoftaki - Journal of Proteome Research, 2023 - ACS Publications
Imaging mass spectrometry is a well-established technology that can easily and succinctly
communicate the spatial localization of molecules within samples. This review …
communicate the spatial localization of molecules within samples. This review …
[HTML][HTML] Plasma metabolome signatures to predict responsiveness to neoadjuvant chemotherapy in breast cancer
AAR Silva, MR Cardoso, DC Oliveira, P Godoy… - Cancers, 2024 - mdpi.com
Simple Summary Neoadjuvant chemotherapy (NACT) is a pivotal treatment for breast cancer
(BC). However, the success of NACT is uncertain and dependent on BC subtype. A valuable …
(BC). However, the success of NACT is uncertain and dependent on BC subtype. A valuable …
Mass-spectrometry-based lipidomics discriminates specific changes in lipid classes in healthy and dyslipidemic adults
Triacylglycerols (TAGs) and cholesterol lipoprotein levels are widely used to predict
cardiovascular risk and metabolic disorders. The aim of this study is to determine how the …
cardiovascular risk and metabolic disorders. The aim of this study is to determine how the …
Serum Lipidome Profiling Reveals a Distinct Signature of Ovarian Cancer in Korean Women
Background: Distinguishing ovarian cancer from other gynecological malignancies is crucial
for patient survival yet hindered by non-specific symptoms and limited understanding of …
for patient survival yet hindered by non-specific symptoms and limited understanding of …
Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer
TM Bergsten, SE Levy, KE Zink, HJ Lusk… - Frontiers in Cell and …, 2022 - frontiersin.org
High grade serous ovarian cancer (HGSOC), the most lethal histotype of ovarian cancer,
frequently arises from fallopian tube epithelial cells (FTE). Once transformed, tumorigenic …
frequently arises from fallopian tube epithelial cells (FTE). Once transformed, tumorigenic …
Machine Learning Reveals Lipidome Remodeling Dynamics in a Mouse Model of Ovarian Cancer
Ovarian cancer (OC) is one of the deadliest cancers affecting the female reproductive
system. It may present little or no symptoms at the early stages and typically unspecific …
system. It may present little or no symptoms at the early stages and typically unspecific …
DBDA matrix increases ion abundance of fatty acids and sulfatides in MALDI-TOF and mass spectrometry imaging studies
N Khamidova, MR Pergande… - Journal of the …, 2023 - ACS Publications
MALDI-TOF MS is a powerful tool to analyze biomolecules, owing to its soft ionization nature
that generally results in simple spectra of singly charged ions. Implementation of the …
that generally results in simple spectra of singly charged ions. Implementation of the …
An Early Detection of Ovarian Cancer and The Accurate Spreading Range in Human Body by using Deep Medical Learning Model
V Saravanan, V Sankaradass… - 2023 International …, 2023 - ieeexplore.ieee.org
Current methods of ovarian cancer screening include physical examination, ultrasound, and
blood tests to detect the cancer antagonist (CA-125). All of these are subject to appropriate …
blood tests to detect the cancer antagonist (CA-125). All of these are subject to appropriate …