Noncoding RNA therapeutics—challenges and potential solutions

M Winkle, SM El-Daly, M Fabbri, GA Calin - Nature reviews Drug …, 2021 - nature.com
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

[HTML][HTML] Therapeutic advances of miRNAs: A preclinical and clinical update

C Chakraborty, AR Sharma, G Sharma… - Journal of advanced …, 2021 - Elsevier
Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …

Recent applications of PLGA based nanostructures in drug delivery

M Mir, N Ahmed, A ur Rehman - Colloids and Surfaces B: Biointerfaces, 2017 - Elsevier
Over the years, issues associated with non-biodegradable polymers have paved the way for
biodegradable polymers in the domain of pharmaceutical and biomedical sciences. Poly …

Chitosan-based nanomaterials for drug delivery

J Li, C Cai, J Li, J Li, J Li, T Sun, L Wang, H Wu, G Yu - Molecules, 2018 - mdpi.com
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …

MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …

miRNAs driving diagnosis, progression, and drug resistance in multiple myeloma

MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a tumor of transformed plasma cells. It's the second most common
hematologic cancer after non-Hodgkin lymphoma. MM is a complex disease with many …

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

Application of light scattering techniques to nanoparticle characterization and development

PM Carvalho, MR Felício, NC Santos… - Frontiers in …, 2018 - frontiersin.org
Over the years, the scientific importance of nanoparticles for biomedical applications has
increased. The high stability and biocompatibility, together with the low toxicity of the …

Non-ionic surfactants for stabilization of polymeric nanoparticles for biomedical uses

H Cortés, H Hernández-Parra, SA Bernal-Chávez… - Materials, 2021 - mdpi.com
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …

Mucosal applications of poloxamer 407-based hydrogels: An overview

E Giuliano, D Paolino, M Fresta, D Cosco - Pharmaceutics, 2018 - mdpi.com
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …