Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
How the ligand field in lanthanide coordination complexes determines magnetic susceptibility anisotropy, paramagnetic NMR shift, and relaxation behavior
Conspectus Complexes of lanthanide (III) ions are being actively studied because of their
unique ground and excited state properties and the associated optical and magnetic …
unique ground and excited state properties and the associated optical and magnetic …
Lanthanide probes for bioresponsive imaging
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
Molecular magnetic resonance imaging with Gd (III)-based contrast agents: challenges and key advances
In an era of personalized medicine, the clinical community has become increasingly focused
on understanding diseases at the cellular and molecular levels. Magnetic resonance …
on understanding diseases at the cellular and molecular levels. Magnetic resonance …
Using lanthanide ions in molecular bioimaging
AJ Amoroso, SJA Pope - Chemical Society Reviews, 2015 - pubs.rsc.org
Trivalent lanthanide ions offer remarkable opportunities in the design of bioimaging agents:
this review presents an accessible discussion of their application in both optical and …
this review presents an accessible discussion of their application in both optical and …
Molecular imaging for cancer diagnosis and surgery
T Hussain, QT Nguyen - Advanced drug delivery reviews, 2014 - Elsevier
Novel molecular imaging techniques have the potential to significantly enhance the
diagnostic and therapeutic approaches for cancer treatment. For solid tumors in particular …
diagnostic and therapeutic approaches for cancer treatment. For solid tumors in particular …
Classification and basic properties of contrast agents for magnetic resonance imaging
A comprehensive classification of contrast agents currently used or under development for
magnetic resonance imaging (MRI) is presented. Agents based on small chelates …
magnetic resonance imaging (MRI) is presented. Agents based on small chelates …
Being excited by lanthanide coordination complexes: aqua species, chirality, excited-state chemistry, and exchange dynamics
Over the past 10 years there has been a resurgence of interest in the coordination chemistry
of lanthanide complexes in aqueous solution. Excitement in this work may be related to an …
of lanthanide complexes in aqueous solution. Excitement in this work may be related to an …
PARACEST agents: modulating MRI contrast via water proton exchange
S Zhang, M Merritt, DE Woessner… - Accounts of chemical …, 2003 - ACS Publications
Scientific interest in optimizing the properties of gadolinium (III) complexes as MRI contrast
agents has led to many new insights into lanthanide ion coordination chemistry in the last …
agents has led to many new insights into lanthanide ion coordination chemistry in the last …
Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging
Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …