Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Disordered regions tune order in chromatin organization and function
Intrinsically disordered proteins or hybrid proteins with ordered domains and disordered
regions (both collectively designated as IDP (R) s) defy the well-established structure …
regions (both collectively designated as IDP (R) s) defy the well-established structure …
Integrating single-molecule FRET and biomolecular simulations to study diverse interactions between nucleic acids and proteins
The conformations of biological macromolecules are intimately related to their cellular
functions. Conveniently, the well-characterized dipole–dipole distance-dependence of …
functions. Conveniently, the well-characterized dipole–dipole distance-dependence of …
Tuning formation of protein–DNA coacervates by sequence and environment
The high concentration of nucleic acids and positively charged proteins in the cell nucleus
provides many possibilities for complex coacervation. We consider a prototypical mixture of …
provides many possibilities for complex coacervation. We consider a prototypical mixture of …
Integrating single-molecule spectroscopy and simulations for the study of intrinsically disordered proteins
Over the last two decades, intrinsically disordered proteins and protein regions (IDRs) have
emerged from a niche corner of biophysics to be recognized as essential drivers of cellular …
emerged from a niche corner of biophysics to be recognized as essential drivers of cellular …
Binding dynamics of disordered linker histone H1 with a nucleosomal particle
Linker histone H1 is an essential regulatory protein for many critical biological processes,
such as eukaryotic chromatin packaging and gene expression. Mis-regulation of H1s is …
such as eukaryotic chromatin packaging and gene expression. Mis-regulation of H1s is …
Single-molecule conformational dynamics of a transcription factor reveals a continuum of binding modes controlling association and dissociation
Binding and unbinding of transcription factors to DNA are kinetically controlled to regulate
the transcriptional outcome. Control of the release of the transcription factor NF-κB from DNA …
the transcriptional outcome. Control of the release of the transcription factor NF-κB from DNA …
Extended and dynamic linker histone-DNA Interactions control chromatosome compaction
Chromatosomes play a fundamental role in chromatin regulation, but a detailed
understanding of their structure is lacking, partially due to their complex dynamics. Using …
understanding of their structure is lacking, partially due to their complex dynamics. Using …
DNA sequence-dependent positioning of the linker histone in a nucleosome: A single-pair FRET study
Linker histones (LHs) bind to nucleosomes with their globular domain (gH) positioned in
either an on-or an off-dyad binding mode. Here, we study the effect of the linker DNA (L …
either an on-or an off-dyad binding mode. Here, we study the effect of the linker DNA (L …
In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays
Histone proteins associate with DNA to form the eukaryotic chromatin. The basic unit of
chromatin is a nucleosome, made up of a histone octamer consisting of two copies of the …
chromatin is a nucleosome, made up of a histone octamer consisting of two copies of the …
Protein intrinsic disorder on a dynamic nucleosomal landscape
The complex nucleoprotein landscape of the eukaryotic cell nucleus is rich in dynamic
proteins that lack a stable three-dimensional structure. Many of these intrinsically disordered …
proteins that lack a stable three-dimensional structure. Many of these intrinsically disordered …