Potential targeted therapy and diagnosis based on novel insight into growth factors, receptors, and downstream effectors in acute kidney injury and acute kidney injury …

LI Gao, X Zhong, J **, J Li, X Meng - Signal transduction and targeted …, 2020 - nature.com
Acute kidney injury (AKI) is defined as a rapid decline in renal function and is characterized
by excessive renal inflammation and programmed death of resident cells. AKI shows high …

Body fluid-derived stem cells—an untapped stem cell source in genitourinary regeneration

RL Huang, Q Li, JX Ma, A Atala, Y Zhang - Nature Reviews Urology, 2023 - nature.com
Somatic stem cells have been obtained from solid organs and tissues, including the bone
marrow, placenta, corneal stroma, periosteum, adipose tissue, dental pulp and skeletal …

Optimization strategies of mesenchymal stem cell-based therapy for acute kidney injury

Z Fu, Y Zhang, X Geng, K Chi, C Liu, C Song… - Stem Cell Research & …, 2023 - Springer
Considering the high prevalence and the lack of targeted pharmacological management of
acute kidney injury (AKI), the search for new therapeutic approaches for it is in urgent …

The regenerative potential of amniotic fluid stem cell extracellular vesicles: lessons learned by comparing different isolation techniques

L Antounians, A Tzanetakis, O Pellerito, VD Catania… - Scientific reports, 2019 - nature.com
Extracellular vesicles (EVs) derived from amniotic fluid stem cells (AFSCs) mediate anti-
apoptotic, pro-angiogenic, and immune-modulatory effects in multiple disease models, such …

Stem/stromal cells for treatment of kidney injuries with focus on preclinical models

A Torres Crigna, C Daniele, C Gamez… - Frontiers in …, 2018 - frontiersin.org
Within the last years, the use of stem cells (embryonic, induced pluripotent stem cells, or
hematopoietic stem cells), Progenitor cells (eg, endothelial progenitor cells), and most …

Mesenchymal stem cell-derived extracellular vesicles: a potential therapeutic strategy for acute kidney injury

JK Li, C Yang, Y Su, JC Luo, MH Luo… - Frontiers in …, 2021 - frontiersin.org
Acute kidney injury (AKI) is a common and potential life-threatening disease in patients
admitted to hospital, affecting 10%–15% of all hospitalizations and around 50% of patients …

[HTML][HTML] De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells

FO Arcolino, S Hosgood, S Akalay, N Jordan… - American Journal of …, 2022 - Elsevier
During development, nephron structures are derived from a SIX2+ stem cell population. After
36 weeks of gestation, these cells are exhausted, and no new nephrons are formed. We …

Barriers and advances in kidney preservation

C Steichen, S Giraud, D Bon, B Barrou… - BioMed research …, 2018 - Wiley Online Library
Despite the fact that a significant fraction of kidney graft dysfunctions observed after
transplantation is due to ischemia‐reperfusion injuries, there is still no clear consensus …

Upregulation of vascular endothelial growth factor in amniotic fluid stem cells enhances their potential to attenuate lung injury in a preterm rabbit model of …

J Jiménez, F Lesage, J Richter, T Nagatomo, T Salaets… - Neonatology, 2018 - karger.com
Background: Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects
extremely preterm infants and remains–despite improvements in neonatal intensive care–a …

Effect of human amniotic fluid stem cells on kidney function in a model of chronic kidney disease

SK George, M Abolbashari, TH Kim… - … Engineering Part A, 2019 - liebertpub.com
Kidney disease is a major medical problem globally. Chronic kidney disease (CKD) is a
progressive loss of kidney function. It causes accumulation of waste and fluid in the body …