[HTML][HTML] Corneal structure and transparency

KM Meek, C Knupp - Progress in retinal and eye research, 2015 - Elsevier
The corneal stroma plays several pivotal roles within the eye. Optically, it is the main
refracting lens and thus has to combine almost perfect transmission of visible light with …

Composition, structure and function of the corneal stroma

EM Espana, DE Birk - Experimental eye research, 2020 - Elsevier
No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts

M Rafat, M Jabbarvand, N Sharma, M Xeroudaki… - Nature …, 2023 - nature.com
Visual impairment from corneal stromal disease affects millions worldwide. We describe a
cell-free engineered corneal tissue, bioengineered porcine construct, double crosslinked …

Light‐activated decellularized extracellular matrix‐based bioinks for volumetric tissue analogs at the centimeter scale

H Kim, B Kang, X Cui, SH Lee, K Lee… - Advanced Functional …, 2021 - Wiley Online Library
Tissue engineering requires not only tissue‐specific functionality but also a realistic scale.
Decellularized extracellular matrix (dECM) is presently applied to the extrusion‐based 3D …

Collagen tissue engineering: development of novel biomaterials and applications

L Cen, WEI Liu, LEI Cui, W Zhang, Y Cao - Pediatric research, 2008 - nature.com
Scientific investigations involving collagen have inspired tissue engineering and design of
biomaterials since collagen fibrils and their networks primarily regulate and define most …

[LIBRO][B] Adler's Physiology of the Eye: Expert Consult-Online and Print

LA Levin, SFE Nilsson, J Ver Hoeve, S Wu… - 2011 - books.google.com
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv FE Nilsson, James Ver Hoeve, and
Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye …

[HTML][HTML] A double-crosslinked nanocellulose-reinforced dexamethasone-loaded collagen hydrogel for corneal application and sustained anti-inflammatory activity

M Xeroudaki, M Rafat, P Moustardas, A Mukwaya… - Acta biomaterialia, 2023 - Elsevier
In cases of blinding disease or trauma, hydrogels have been proposed as scaffolds for
corneal regeneration and vehicles for ocular drug delivery. Restoration of corneal …

Biomechanical characterization of keratoconus corneas ex vivo with Brillouin microscopy

G Scarcelli, S Besner, R Pineda… - … ophthalmology & visual …, 2014 - iovs.arvojournals.org
Purpose.: Loss of corneal strength is a central feature of keratoconus progression. However,
it is currently difficult to measure corneal mechanical changes noninvasively. The objective …

What biomechanical properties of the cornea are relevant for the clinician?

A Kotecha - Survey of ophthalmology, 2007 - Elsevier
Although the effects of central corneal thickness and corneal curvature on intraocular
pressure measurement are well known, it has only recently become possible to measure the …

Human limbal biopsy–derived stromal stem cells prevent corneal scarring

S Basu, AJ Hertsenberg, ML Funderburgh… - Science translational …, 2014 - science.org
Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …