Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD)–revised recommendations of the Neuromyelitis Optica Study Group …
T Kümpfel, K Giglhuber, O Aktas, I Ayzenberg… - Journal of …, 2024 - Springer
This manuscript presents practical recommendations for managing acute attacks and
implementing preventive immunotherapies for neuromyelitis optica spectrum disorders …
implementing preventive immunotherapies for neuromyelitis optica spectrum disorders …
[HTML][HTML] A comprehensive review of the advances in neuromyelitis optica spectrum disorder
Neuromyelitis optica spectrum disorder (NMOSD) is a rare relapsing neuroinflammatory
autoimmune astrocytopathy, with a predilection for the optic nerves and spinal cord. Most …
autoimmune astrocytopathy, with a predilection for the optic nerves and spinal cord. Most …
Long‐term safety and efficacy of Eculizumab in Aquaporin‐4 IgG‐positive NMOSD
DM Wingerchuk, K Fujihara, J Palace… - Annals of …, 2021 - Wiley Online Library
Objective During PREVENT (NCT01892345), eculizumab significantly reduced relapse risk
versus placebo in patients with aquaporin‐4 immunoglobulin G‐positive neuromyelitis …
versus placebo in patients with aquaporin‐4 immunoglobulin G‐positive neuromyelitis …
Progress in treatment of Neuromyelitis Optica Spectrum Disorders (NMOSD): Novel insights into therapeutic possibilities in NMOSD
M Shi, F Chu, T **, J Zhu - CNS Neuroscience & Therapeutics, 2022 - Wiley Online Library
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory
demyelinating disorder of the central nervous system (CNS), which is a severely disabling …
demyelinating disorder of the central nervous system (CNS), which is a severely disabling …
The role of complement and complement therapeutics in neuromyelitis optica spectrum disorders
Introduction Neuromyelitis optica spectrum disorders (NMOSD) are characterized in the
majority of cases by the presence of IgG1 autoantibodies against aquaporin 4 (AQP4) and …
majority of cases by the presence of IgG1 autoantibodies against aquaporin 4 (AQP4) and …
Eculizumab use in neuromyelitis optica spectrum disorders: routine clinical care data from a European cohort
M Ringelstein, S Asseyer, G Lindenblatt, K Fischer… - Neurology, 2024 - neurology.org
Background and Objectives Attack prevention is crucial in managing neuromyelitis optica
spectrum disorders (NMOSDs). Eculizumab (ECU), an inhibitor of the terminal complement …
spectrum disorders (NMOSDs). Eculizumab (ECU), an inhibitor of the terminal complement …
In utero exposure to maternal anti–aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring
S Mader, L Brimberg, A Vo, JJ Strohl… - Science translational …, 2022 - science.org
The fetal brain is constantly exposed to maternal IgG before the formation of an effective
blood-brain barrier (BBB). Here, we studied the consequences of fetal brain exposure to an …
blood-brain barrier (BBB). Here, we studied the consequences of fetal brain exposure to an …
Ravulizumab in Aquaporin‐4–Positive Neuromyelitis Optica Spectrum Disorder
Objective CHAMPION‐NMOSD (NCT04201262) is a phase 3, open‐label, externally
controlled interventional study evaluating the efficacy and safety of the terminal complement …
controlled interventional study evaluating the efficacy and safety of the terminal complement …
Adverse events in NMOSD therapy
K Giglhuber, A Berthele - International journal of molecular sciences, 2022 - mdpi.com
Neuromyelitis optica spectrum disorders (NMOSD) are rare neurologic autoimmune
diseases that have a poor prognosis if left untreated. For many years, generic oral …
diseases that have a poor prognosis if left untreated. For many years, generic oral …
Comparisons of clinical phenotype, radiological and laboratory features, and therapy of neuromyelitis optica spectrum disorder by regions: update and challenges
C Liu, M Shi, M Zhu, F Chu, T **, J Zhu - Autoimmunity Reviews, 2022 - Elsevier
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disease
of the central nervous system (CNS) associated with autoantibody (ab) to aquaporin-4 …
of the central nervous system (CNS) associated with autoantibody (ab) to aquaporin-4 …