Sex differences in cellular and systems biology have been evolutionarily selected to
optimize reproductive success in all species with little (sperm) and big (ova) gamete …

Since the first polygenic risk score (PRS) in 2007, research in this area has progressed
significantly. The increasing number of SNPs that have been identified by large scale GWAS …

# 1 International Bestseller “A rallying cry to fight back.”—Sunday Times (London) Winner,
2019 Financial Times and McKinsey Business Book of the Year Award Winner, 2019 Royal …

A little over 5 years ago, the US National Institutes of Health (NIH) announced the intention
to develop policies to require applicants to report plans to balance male and female cells …

Research into the microbiota–gut–brain axis (MGBA) has entered a golden age, raising the
hope that therapeutics acting on it may offer breakthroughs in the treatment of many …

Until the last quarter of the 20th century, sex was not recognized as a variable in health
research, nor was it believed to be a factor that could affect health and illness. Researchers …

There are prominent sex/gender differences in the prevalence, expression, and life span
course of mental health and neurodiverse conditions. However, the underlying sex-and …

Objective To evaluate sex differences in mortality among people with kidney failure
compared with the general population. Design Population based cohort study using data …

Medication (drug) use in human pregnancy is prevalent. Determining fetal safety and
efficacy of drugs is logistically challenging. However, predicting (not measuring) fetal drug …

Background Despite initiatives to promote equal enrollment of human subjects in clinical
trials, females continue to be underrepresented. The goal of this work is to determine if …