Integrons were first identified because of their central role in assembling and disseminating
antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically …

Integrons are flexible gene-exchanging platforms that contain multiple cassettes encoding
accessory genes whose order is shuffled by a specific integrase. Integrons embedded within …

Biological technologies are fundamentally unlike any other because biology evolves.
Bioengineering therefore requires novel design methodologies with evolution at their core …

Plant microbiomes play important roles in plant health and fitness. Bacterial horizontal gene
transfer (HGT) can influence plant health outcomes, driving the spread of both plant growth …

Horizontal gene transfer between different domains of life is increasingly being recognized
as an important evolutionary driver, with the potential to increase the pace of biochemical …

Integrons are bacterial genetic elements that can capture mobile gene cassettes. They are
mostly known for their role in the spread of antibiotic resistance cassettes, contributing …

The objective of this study is to identify and analyze integrons and antibiotic resistance
genes (ARGs) in samples collected from diverse sites in terrestrial Antarctica. Integrons were …

Solid-state nanopore-based electrical detection of DNA nucleotides with the quantum
tunneling technique has emerged as a powerful strategy to be the next-generation …

Multiple antibiotic resistances are a major global health threat. The predominant tool for
adaptation in Gram-negative bacteria is the integron. Under stress, it rearranges gene …

Bacteriophages are versatile mobile genetic elements that play key roles in driving the
evolution of their bacterial hosts through horizontal gene transfer. Phages co-evolve with …