Tumor biomarkers for diagnosis, prognosis and targeted therapy

Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - Signal transduction and …, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Recent advances in organic near-infrared ratiometric small-molecule fluorescent probes

YL Qi, YZ Li, MJ Tan, FF Yuan, N Murthy… - Coordination Chemistry …, 2023 - Elsevier
The burgeoning organic near-infrared (NIR) ratiometric small-molecule fluorescent probes
with excellent merits have attracted great attention over the past few years. The traditional …

Deep insight of design, mechanism, and cancer theranostic strategy of nanozymes

L Yang, S Dong, S Gai, D Yang, H Ding, L Feng… - Nano-Micro Letters, 2024 - Springer
Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007, nanozymes are
becoming the promising substitutes for natural enzymes due to their advantages of high …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

Ratiometric fluorescent signals-driven smartphone-based portable sensors for onsite visual detection of food contaminants

Y Shen, Y Wei, C Zhu, J Cao, DM Han - Coordination Chemistry Reviews, 2022 - Elsevier
Abstract Development of efficient and portable biosensor to achieve the accurate onsite
detection of food contaminants is of very great significance for safeguarding food safety and …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Bienzyme-locked activatable fluorescent probes for specific imaging of tumor-associated mast cells

Y Hu, J Yu, M Xu, K Pu - Journal of the American Chemical …, 2024 - ACS Publications
Tumor-associated mast cells (TAMCs) have been recently revealed to play a multifaceted
role in the tumor microenvironment. Noninvasive optical imaging of TAMCs is thus highly …

Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY **e - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Organelle-targeting ratiometric fluorescent probes: design principles, detection mechanisms, bio-applications, and challenges

MK Goshisht, N Tripathi, GK Patra, M Chaskar - Chemical Science, 2023 - pubs.rsc.org
Biological species, including reactive oxygen species (ROS), reactive sulfur species (RSS),
reactive nitrogen species (RNS), F−, Pd2+, Cu2+, Hg2+, and others, are crucial for the …