Cellular and molecular mechanisms of kidney fibrosis
Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …
injury or maladaptive repair. It is considered as the underlying pathological process of …
Mechanisms of renal fibrosis
BD Humphreys - Annual review of physiology, 2018 - annualreviews.org
Tubulointerstitial fibrosis is a chronic and progressive process affecting kidneys during aging
and in chronic kidney disease (CKD), regardless of cause. CKD and renal fibrosis affect half …
and in chronic kidney disease (CKD), regardless of cause. CKD and renal fibrosis affect half …
Extracellular matrix in kidney fibrosis: more than just a scaffold
Kidney fibrosis is the common histological end-point of progressive, chronic kidney diseases
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
The good and the bad collagens of fibrosis–their role in signaling and organ function
Usually the dense extracellular structure in fibrotic tissues is described as extracellular
matrix (ECM) or simply as collagen. However, fibrosis is not just fibrosis, which is already …
matrix (ECM) or simply as collagen. However, fibrosis is not just fibrosis, which is already …
[HTML][HTML] Cellular and molecular probing of intact human organs
Optical tissue transparency permits scalable cellular and molecular investigation of complex
tissues in 3D. Adult human organs are particularly challenging to render transparent …
tissues in 3D. Adult human organs are particularly challenging to render transparent …
Collagen biology and non‐invasive biomarkers of liver fibrosis
There is an unmet need for high‐quality liquid biomarkers that can safely and reproducibly
predict the stage of fibrosis and the outcomes of chronic liver disease (CLD). The …
predict the stage of fibrosis and the outcomes of chronic liver disease (CLD). The …
Targeting renal fibrosis: mechanisms and drug delivery systems
MV Nastase, J Zeng-Brouwers, M Wygrecka… - Advanced drug delivery …, 2018 - Elsevier
Renal fibrosis is the common outcome of many chronic kidney diseases (CKD) independent
of the underlying etiology. Despite a host of promising experimental data, currently available …
of the underlying etiology. Despite a host of promising experimental data, currently available …
[HTML][HTML] Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use
Osteoarthritis (OA) is a heterogeneous disorder. The goals of this review are (1) To stimulate
use of standardized nomenclature for OA that could serve as building blocks for describing …
use of standardized nomenclature for OA that could serve as building blocks for describing …
Radiation-induced kidney toxicity: molecular and cellular pathogenesis
R Klaus, M Niyazi, B Lange-Sperandio - Radiation oncology, 2021 - Springer
Radiation nephropathy (RN) is a kidney injury induced by ionizing radiation. In a clinical
setting, ionizing radiation is used in radiotherapy (RT). The use and the intensity of radiation …
setting, ionizing radiation is used in radiotherapy (RT). The use and the intensity of radiation …
Kidney fibrosis: Emerging diagnostic and therapeutic strategies
BM Klinkhammer, P Boor - Molecular Aspects of Medicine, 2023 - Elsevier
An increasing number of patients worldwide suffers from chronic kidney disease (CKD).
CKD is accompanied by kidney fibrosis, which affects all compartments of the kidney, ie, the …
CKD is accompanied by kidney fibrosis, which affects all compartments of the kidney, ie, the …