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Design of artificial biomimetic channels with Na+ permeation rate and selectivity potentially outperforming the natural sodium channel
Artificial ion channels that enable high-efficiency ion transport have important implications in
nanofluidics and biomedical applications such as drug delivery. Herein, we show a …
nanofluidics and biomedical applications such as drug delivery. Herein, we show a …
Effect of cholesterol on the membrane partitioning dynamics of hepatitis A virus-2B peptide
Understanding viral peptide detection and partitioning and the subsequent host membrane
composition-based response is essential for gaining insights into the viral mechanism. Here …
composition-based response is essential for gaining insights into the viral mechanism. Here …
[HTML][HTML] Microsecond simulation of human aquaporin 2 reveals structural determinants of water permeability and selectivity
Abstract Human aquaporin 2 (AQP2) from the family of aquaporins assumes great
physiological importance, owing to its association with nephrogenic diabetes insipidus …
physiological importance, owing to its association with nephrogenic diabetes insipidus …
Assessing the physiological relevance of alternate architectures of the p7 protein of hepatitis C virus in different environments
The viroporin p7 of the hepatitis C virus forms multimeric channels eligible for ion transport
across the endoplasmic reticulum membrane. Currently the subject of many studies and …
across the endoplasmic reticulum membrane. Currently the subject of many studies and …
Urea–aromatic stacking and concerted urea transport: conserved mechanisms in urea transporters revealed by molecular dynamics
Urea transporters are membrane proteins that selectively allow urea molecules to pass
through. It is not clear how these transporters allow rapid conduction of urea, a polar …
through. It is not clear how these transporters allow rapid conduction of urea, a polar …
Resonance-driven ion transport and selectivity in prokaryotic ion channels
Ion channels exhibit a remarkably high accuracy in selecting uniquely its associated type of
ion. The mechanisms behind ion selectivity are not well understood. Current explanations …
ion. The mechanisms behind ion selectivity are not well understood. Current explanations …
Ion Selectivity and Permeation Mechanism in a Cyclodextrin-Based Channel
Synthetic ion channels are a promising technology in the medical and materials sciences
because of their ability to conduct ions. Channels based on cyclodextrin, a cyclic oligomer of …
because of their ability to conduct ions. Channels based on cyclodextrin, a cyclic oligomer of …
Cooperation of hydrophobic gating, knock-on effect, and ion binding determines ion selectivity in the p7 channel
Ion channels selectively allow certain ions to pass through at much higher rates than others,
and thereby modulate ionic concentrations across cell membranes. The current molecular …
and thereby modulate ionic concentrations across cell membranes. The current molecular …
pH-mediated gating and formate transport mechanism in the Escherichia coli formate channel
Formate channels play a crucial role in the metabolism of several different kinds of bacteria
by bringing about uptake and export of formate ions. The current study investigates the …
by bringing about uptake and export of formate ions. The current study investigates the …
[PDF][PDF] Ion Selectivity and Permeation Mechanism in a Cyclodextrin-based Channel
M Pratyusha - 2021 - web2py.iiit.ac.in
Ion channels are proteins present across the lipid bilayer membrane possessing a pore that
selectively allows certain ions to pass through. They control various cellular processes and …
selectively allows certain ions to pass through. They control various cellular processes and …