Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

Advancing the global public health agenda for NAFLD: a consensus statement

JV Lazarus, HE Mark, QM Anstee, JP Arab… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects
approximately one-quarter of the global adult population, causing a substantial burden of ill …

Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement

M Eslam, N Alkhouri, P Vajro, U Baumann… - The Lancet …, 2021 - thelancet.com
The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …

MAFLD enhances clinical practice for liver disease in the Asia-Pacific region

T Kawaguchi, T Tsutsumi, D Nakano… - Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Fatty liver is now a major cause of liver disease in the Asia-Pacific region. Liver diseases in
this region have distinctive characteristics. First, fatty liver is frequently observed in …

Metabolic dysfunction-associated fatty liver disease: a year in review

J Alharthi, A Gastaldelli, IH Cua… - Current Opinion in …, 2022 - journals.lww.com
The transformation in name and definition from NAFLD to MAFLD represents an important
milestone, which indicates significant tangible progress towards a more inclusive, equitable …

Incorporating fatty liver disease in multidisciplinary care and novel clinical trial designs for patients with metabolic diseases

M Eslam, A Ahmed, JP Després, V Jha… - The Lancet …, 2021 - thelancet.com
With the global epidemics of obesity and associated conditions, including type 2 diabetes,
metabolic dysfunction-associated fatty liver disease, chronic kidney disease, hypertension …

Metabolic dysfunction–associated fatty liver disease and the risk of 24 specific cancers

Z Liu, C Lin, C Suo, R Zhao, L **, T Zhang, X Chen - Metabolism, 2022 - Elsevier
Background Metabolic dysfunction-associated fatty liver disease (MAFLD) is a significant
health issue closely associated with multiple metabolic dysfunctions. The association …

Comparing the diagnostic criteria of MAFLD and NAFLD in the Chinese population: a population-based prospective cohort study

C Yu, M Wang, S Zheng, M **a, H Yang… - Journal of clinical …, 2021 - pmc.ncbi.nlm.nih.gov
Background and Aims Metabolic dysfunction-associated fatty liver disease (MAFLD) is a
new concept, proposed in 2020; however, its applicability in Asia populations has yet to be …

NAFLD and vitamin D: Evidence for intersection of microRNA-regulated pathways

Z Zhang, R Moon, JL Thorne… - Nutrition Research …, 2023 - cambridge.org
Non-alcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver
disease, worldwide. The molecular pathogenesis of NAFLD is complex, involving numerous …

The NAFLD‐MAFLD debate: Is there a Consensus‐on‐Consensus methodology?

Y Fouad, JF Dufour, MH Zheng, S Bollipo… - Liver …, 2022 - Wiley Online Library
Polarizing opinions have recently arisen in hepatology on the name and redefinition of fatty
liver disease associated with metabolic dysfunction. In spite of growing and robust evidence …