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Therapeutic advances of targeting receptor tyrosine kinases in cancer
Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained
significant clinical attention in oncology due to their central role in cancer pathogenesis …
significant clinical attention in oncology due to their central role in cancer pathogenesis …
[HTML][HTML] Artificial intelligence in digital pathology for bladder cancer: hype or hope? A systematic review
Simple Summary The diagnosis and prediction of prognosis for bladder cancer (BC) can be
challenging because of the subjective nature of pathological evaluation. Artificial …
challenging because of the subjective nature of pathological evaluation. Artificial …
Choline phosphate-grafted nanozymes as universal extracellular vesicle probes for bladder cancer detection
Q Li, S Zhan, X Yang, Z Zhang, N Sun, X Wang… - ACS …, 2024 - ACS Publications
Urinary extracellular vesicles (uEVs) are regarded as highly promising liquid-biopsy
biomarkers for the early diagnosis and prognosis of bladder cancer (BC). However …
biomarkers for the early diagnosis and prognosis of bladder cancer (BC). However …
[PDF][PDF] Bladder cancer and artificial intelligence: emerging applications
AI holds strong potential to guide decision-making for BC diagnosis and treatment and to
integrate such models into the current clinical workflow. This review summarizes the …
integrate such models into the current clinical workflow. This review summarizes the …
Revisiting treatment of metastatic urothelial cancer: where do cisplatin and platinum ineligibility criteria stand?
MJ Moussa, MT Campbell, O Alhalabi - Biomedicines, 2024 - mdpi.com
Cisplatin-based chemotherapy has been the standard of care in metastatic urothelial cancer
(mUC) for more than two decades. However, many patients with comorbidities cannot …
(mUC) for more than two decades. However, many patients with comorbidities cannot …
Treatment approaches for FGFR-altered urothelial carcinoma: targeted therapies and immunotherapy
DJ Benjamin, R Hsu - Frontiers in Immunology, 2023 - frontiersin.org
The treatment of metastatic urothelial carcinoma has dramatically changed over the past
decade with the approval of several therapies from multiple drug classes including immune …
decade with the approval of several therapies from multiple drug classes including immune …
Comprehensive Overview of Interface Strategies in Implant Osseointegration
X Lu, Y Zhao, X Peng, C Lu, Z Wu, H Xu… - Advanced Functional …, 2024 - Wiley Online Library
With the improvement of implant design and the expansion of application scenarios,
orthopedic implants have become a common surgical option for treating fractures and end …
orthopedic implants have become a common surgical option for treating fractures and end …
Discovery of TYRA-300: first oral selective FGFR3 inhibitor for the treatment of urothelial cancers and achondroplasia
RL Hudkins, E Allen, A Balcer, ID Hoffman… - Journal of Medicinal …, 2024 - ACS Publications
Activating FGFR3 alterations have been identified in up to 15–20% of muscle-invasive
bladder cancer and metastatic urothelial carcinoma (mUC), and as high as 80% in …
bladder cancer and metastatic urothelial carcinoma (mUC), and as high as 80% in …
The role of TERT C228T and KDM6A alterations and TME in NMIBC treated with BCG
We aimed to investigate the genomic and tumor microenvironmental (TME) profiles in non-
muscle invasive bladder cancer (NMIBC) and explore potential predictive markers for …
muscle invasive bladder cancer (NMIBC) and explore potential predictive markers for …
The evolving treatment landscape of metastatic urothelial cancer
Cisplatin-based chemotherapy is currently the first-line standard of care for patients with
metastatic urothelial cancer (mUC); however, up to 50% of patients are ineligible for …
metastatic urothelial cancer (mUC); however, up to 50% of patients are ineligible for …