Anthropometric and physiological predispositions for elite soccer

T Reilly, J Bangsbo, A Franks - Journal of sports sciences, 2000 - Taylor & Francis
This review is focused on anthropometric and physiological characteristics of soccer players
with a view to establishing their roles within talent detection, identification and development …

Molecular mechanisms of human hypertension

RP Lifton, AG Gharavi, DS Geller - Cell, 2001 - cell.com
Hypertension, or elevated arterial blood pressure, is a been operationally defined as the
blood pressure level substantial public health problem, affecting 25% of the above which …

Molecular basis of human hypertension: role of angiotensinogen

X Jeunemaitre, F Soubrier, YV Kotelevtsev, RP Lifton… - Cell, 1992 - cell.com
Essential hypertension is a common human disease believed to reautt from the interplay of
multiple genetic and environmental determinants. In genetic studies of two large panels of …

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

F Cambien, O Poirier, L Lecerf, A Evans, JP Cambou… - Nature, 1992 - nature.com
FACTORS involved in the pathogenesis of atherosclerosis, thrombosis and
vasoconstriction1, 2 contribute to the development of coronary heart disease. In a study …

Genetic associations with human longevity at the APOE and ACE loci

F Schächter, L Faure-Delanef, F Guénot, H Rouger… - Nature …, 1994 - nature.com
In an effort to dissect the genetic components of longevity, we have undertaken case–control
studies of populations of centenarians (n= 338) and adults aged 20–70 years at several …

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

S Valitutti, S Müller, M Cella, E Padovan… - Nature, 1995 - nature.com
T LYMPHOCYTES can recognize and be activated by a very small number of complexes of
peptide with major histocompatibility complex (MHC) molecules displayed on the surface of …

Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.

A Bonnardeaux, E Davies, X Jeunemaitre, I Fery… - …, 1994 - Am Heart Assoc
We conducted the present study to determine whether the angiotensin II type I receptor
(AT1) gene might be implicated in human essential hypertension by using case-control and …

ACE Polymorphisms

FA Sayed-Tabatabaei, BA Oostra, A Isaacs… - Circulation …, 2006 - Am Heart Assoc
Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems,
one leading to the production of angiotensin II and the other to the degradation of …

A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme

KE Bernstein, FS Ong, WLB Blackwell, KH Shah… - Pharmacological …, 2013 - Elsevier
Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for
converting angiotensin I into the vasoconstrictor angiotensin II. However, ACE is a relatively …

The ACE gene and human performance: 12 years on

Z Puthucheary, JRA Skipworth, J Rawal, M Loosemore… - Sports medicine, 2011 - Springer
Some 12 years ago, a polymorphism of the angiotensin I-converting enzyme (ACE) gene
became the first genetic element shown to impact substantially on human physical …