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Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y **e, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives
S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …
specific metabolites with widely varying structures that help them adapt to variable survival …
Impacts of large herbivores on terrestrial ecosystems
Large herbivores play unique ecological roles and are disproportionately imperiled by
human activity. As many wild populations dwindle towards extinction, and as interest grows …
human activity. As many wild populations dwindle towards extinction, and as interest grows …
Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …
numerous biotechnological applications. The NP discovery process is expensive and time …
Medicinal plants meet modern biodiversity science
CC Davis, P Choisy - Current Biology, 2024 - cell.com
Plants have been an essential source of human medicine for millennia. In this review, we
argue that a holistic, interdisciplinary approach to the study of medicinal plants that …
argue that a holistic, interdisciplinary approach to the study of medicinal plants that …
Development of a widely targeted volatilomics method for profiling volatilomes in plants
H Yuan, G Cao, X Hou, M Huang, P Du, T Tan, Y Zhang… - Molecular Plant, 2022 - cell.com
Volatile organic compounds play essential roles in plant environment interactions as well as
determining the fragrance of plants. Although gas chromatography-mass spectrometry …
determining the fragrance of plants. Although gas chromatography-mass spectrometry …
Plant metabolic gene clusters in the multi-omics era
Secondary metabolism in plants gives rise to a vast array of small-molecule natural
products. The discovery of operon-like gene clusters in plants has provided a new …
products. The discovery of operon-like gene clusters in plants has provided a new …
Natural history–guided omics reveals plant defensive chemistry against leafhopper pests
Although much is known about plant traits that function in nonhost resistance against
pathogens, little is known about nonhost resistance against herbivores, despite its …
pathogens, little is known about nonhost resistance against herbivores, despite its …
[HTML][HTML] Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects
S Ma, J Li, L Pei, N Feng, Y Zhang - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Similar to blood, interstitial fluid (ISF) contains exogenous drugs and biomarkers and may
therefore substitute blood in drug analysis. However, current ISF extraction techniques …
therefore substitute blood in drug analysis. However, current ISF extraction techniques …
Using synthetic biology to understand the function of plant specialized metabolites
Y Bai, X Liu, IT Baldwin - Annual Review of Plant Biology, 2024 - annualreviews.org
Plant specialized metabolites (PSMs) are variably distributed across taxa, tissues, and
ecological contexts; this variability has inspired many theories about PSM function, which to …
ecological contexts; this variability has inspired many theories about PSM function, which to …