Role of hippo pathway-YAP/TAZ signaling in angiogenesis

GTK Boopathy, W Hong - Frontiers in cell and developmental biology, 2019 - frontiersin.org
Angiogenesis is a highly coordinated process of formation of new blood vessels from pre-
existing blood vessels. The process of development of the proper vascular network is a …

The potential role of hydrogen sulfide in cancer cell apoptosis

W Gao, YF Liu, YX Zhang, Y Wang, YQ **… - Cell Death …, 2024 - nature.com
For a long time, hydrogen sulfide (H2S) has been considered a toxic compound, but recent
studies have found that H2S is the third gaseous signaling molecule which plays a vital role …

The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

JI Jun, LF Lau - Nature cell biology, 2010 - nature.com
Cellular senescence is a recognized mechanism of tumour suppression; however, its
contribution to other pathologies is not well understood. We show that the matricellular …

Regulation of wound healing by growth factors and cytokines

S Werner, R Grose - Physiological reviews, 2003 - journals.physiology.org
Werner, Sabine, and Richard Grose. Regulation of Wound Healing by Growth Factors and
Cytokines. Physiol Rev 83: 835–870, 2003; 10.1152/physrev. 00032.2002.—Cutaneous …

Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets

JI Jun, LF Lau - Nature reviews Drug discovery, 2011 - nature.com
Members of the CCN family of matricellular proteins are crucial for embryonic development
and have important roles in inflammation, wound healing and injury repair in adulthood …

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

HP Gerber, TH Vu, AM Ryan, J Kowalski, Z Werb… - Nature medicine, 1999 - nature.com
Hypertrophic chondrocytes in the epiphyseal growth plate express the angiogenic protein
vascular endothelial growth factor (VEGF). To determine the role of VEGF in endochondral …

Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins

G Bendas, L Borsig - International journal of cell biology, 2012 - Wiley Online Library
Cell adhesion molecules play a significant role in cancer progression and metastasis. Cell‐
cell interactions of cancer cells with endothelium determine the metastatic spread. In …

Matricellular proteins in cardiac adaptation and disease

NG Frangogiannis - Physiological reviews, 2012 - journals.physiology.org
The term matricellular proteins describes a family of structurally unrelated extracellular
macromolecules that, unlike structural matrix proteins, do not play a primary role in tissue …

The insulin-like growth factor-binding protein (IGFBP) superfamily

V Hwa, Y Oh, RG Rosenfeld - Endocrine reviews, 1999 - academic.oup.com
Insulin-Like Growth Factor-Binding Protein (IGFBP) Superfamily* | Endocrine Reviews | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

Extracellular matrix, a hard player in angiogenesis

M Mongiat, E Andreuzzi, G Tarticchio… - International journal of …, 2016 - mdpi.com
The extracellular matrix (ECM) is a complex network of proteins, glycoproteins,
proteoglycans, and polysaccharides. Through multiple interactions with each other and the …