AutoGeneS: Automatic gene selection using multi-objective optimization for RNA-seq deconvolution

H Aliee, FJ Theis - Cell Systems, 2021 - cell.com
Knowing cell-type proportions in a tissue is very important to identify which cells or cell types
are targeted by a disease or perturbation. Hence, several deconvolution methods have been …

[HTML][HTML] Single cell derived mRNA signals across human kidney tumors

MD Young, TJ Mitchell, L Custers, T Margaritis… - Nature …, 2021 - nature.com
Tumor cells may share some patterns of gene expression with their cell of origin, providing
clues into the differentiation state and origin of cancer. Here, we study the differentiation …