In a T1D rat model, depressed sarcoplasmic reticulum function was reported by Penpargkul
et al4 in 1981. Subsequent studies in a T1D mouse model found a significant decrease in …

Patients with diabetes mellitus have> 2× the risk for develo** heart failure (HF; HF with
reduced ejection fraction and HF with preserved ejection fraction). Cardiovascular …

The cardiovascular disease continuum begins with risk factors such as diabetes mellitus
(DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with …

During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent
adducts with the plasma proteins through a non-enzymatic process known as glycation …

Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

Diabetes mellitus increases the risk of heart failure independently of underlying coronary
artery disease, and many believe that diabetes leads to cardiomyopathy. The underlying …

The endoplasmic reticulum (ER) as an intracellular Ca2+ store not only sets up cytosolic
Ca2+ signals, but, among other functions, also assembles and folds newly synthesized …

The presence of a diabetic cardiomyopathy, independent of hypertension and coronary
artery disease, is still controversial. This systematic review seeks to evaluate the evidence …

Diabetes mellitus is an important and prevalent risk factor for congestive heart failure.
Diabetic cardiomyopathy has been defined as ventricular dysfunction that occurs in diabetic …

Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension
and coronary artery disease. Although several molecular mechanisms for the development …