From Subclinical Atherosclerosis to Plaque Progression and Acute Coronary Events: JACC State-of-the-Art Review

A Ahmadi, E Argulian, J Leipsic, DE Newby… - Journal of the American …, 2019 - jacc.org
It has been believed that most acute coronary events result from the rupture of mildly stenotic
plaques, based on studies in which angiographic information was available from many …

Do plaques rapidly progress prior to myocardial infarction? The interplay between plaque vulnerability and progression

A Ahmadi, J Leipsic, R Blankstein, C Taylor… - Circulation …, 2015 - Am Heart Assoc
There is a common misperception in the cardiology community that most acute coronary
events arise from ruptures of mildly stenotic plaques. This notion has emanated from …

Prevalence and characteristics of TCFA and degree of coronary artery stenosis: an OCT, IVUS, and angiographic study

J Tian, H Dauerman, C Toma, H Samady, T Itoh… - Journal of the American …, 2014 - jacc.org
Background: The relationship between features of vulnerable plaque and angiographic
coronary stenosis is unknown. Objectives: The purpose of this study was to systematically …

Invasive and non-invasive assessment of ischaemia in chronic coronary syndromes: translating pathophysiology to clinical practice

OM Demir, H Rahman, TP van de Hoef… - European Heart …, 2022 - academic.oup.com
Intracoronary physiology testing has emerged as a valuable diagnostic approach in the
management of patients with chronic coronary syndrome, circumventing limitations like …

Elevated lipoprotein (a) and low-density lipoprotein cholesterol as predictors of the severity and complexity of angiographic lesions in patients with premature coronary …

D Chieng, J Pang, KL Ellis, GS Hillis, GF Watts… - Journal of Clinical …, 2018 - Elsevier
Background Elevated lipoprotein (a)(Lp [a]) and low-density lipoprotein (LDL) cholesterol
are important inheritable risk factors for premature coronary artery disease (CAD). Lp (a) …

Spatial distribution of vulnerable plaques: comprehensive in vivo coronary plaque map**

M Araki, T Soeda, HO Kim, V Thondapu, M Russo… - Cardiovascular …, 2020 - jacc.org
Objectives The authors performed a comprehensive analysis on the distribution of coronary
plaques with different phenotypes from our 3-vessel optical coherence tomography (OCT) …

High lipoprotein (a) levels predict severity of coronary artery disease in patients hospitalized for acute myocardial infarction. Data from the French RICO survey

M Farnier, F Chagué, M Maza, F Bichat… - Journal of Clinical …, 2022 - Elsevier
Background Lipoprotein (a)(Lp (a)) is a well-recognized independent risk factor for
atherosclerotic cardiovascular disease (ASCVD). However, limited data are available on the …

Association among noncalcified coronary burden, fractional flow reserve, and myocardial injury in psoriasis

W Zhou, KM Abdelrahman, AK Dey… - Journal of the …, 2020 - Am Heart Assoc
Background Myocardial infarction and premature death have been observed in patients with
psoriasis. Although inflammation‐driven accelerated atherosclerosis has been proposed as …

High-risk coronary atheroma: the interplay between ischemia, plaque burden, and disease progression

R Puri, SJ Nicholls, SG Ellis, EM Tuzcu… - Journal of the American …, 2014 - jacc.org
Necropsy studies have outlined the morphological characteristics of high-risk, or
“vulnerable,” coronary plaque segments, demonstrating the presence of inflammatory …

Coronary computed tomography angiography assessment of high-risk plaques in predicting acute coronary syndrome

G Lu, W Ye, J Ou, X Li, Z Tan, T Li, H Liu - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Coronary computed tomography angiography (CCTA) is a comprehensive, non-invasive
and cost-effective imaging assessment approach, which can provide the ability to identify the …