Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Polymeric antibacterial materials: Design, platforms and applications

H Luo, XQ Yin, PF Tan, ZP Gu, ZM Liu… - Journal of Materials …, 2021 - pubs.rsc.org
Over the past decades, the morbidity and mortality caused by pathogen invasion remain
stubbornly high even though medical care has increasingly improved worldwide. Besides …

Peptidomimetic polyurethanes inhibit bacterial biofilm formation and disrupt surface established biofilms

A Vishwakarma, F Dang, A Ferrell… - Journal of the …, 2021 - ACS Publications
Over 80% of all chronic bacterial infections in humans are associated with biofilms, which
are surface-associated bacterial communities encased within a secreted exopolysaccharide …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H **, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

Design of antimicrobial polymers

P Pham, S Oliver, C Boyer - Macromolecular Chemistry and …, 2023 - Wiley Online Library
Antibiotic resistance has become a critical issue, alarming the healthcare and agriculture
sectors worldwide. Thanks to rapid advancements in polymer science, antimicrobial …

Heterochiral β-peptide polymers combating multidrug-resistant cancers effectively without inducing drug resistance

N Shao, L Yuan, P Ma, M Zhou, X **ao… - Journal of the …, 2022 - ACS Publications
Multidrug resistance to chemotherapeutic drugs is one of the major causes for the failure of
cancer treatment. Therefore, there is an urgent need to develop anticancer agents that can …

Polyplex designs for improving the stability and safety of RNA therapeutics

S Uchida, CYJ Lau, M Oba, K Miyata - Advanced Drug Delivery Reviews, 2023 - Elsevier
Nanoparticle-based delivery systems have contributed to the recent clinical success of RNA
therapeutics, including siRNA and mRNA. RNA delivery using polymers has several distinct …

Laser-patterned carbon coatings on flexible and optically transparent plastic substrates for advanced biomedical sensing and implant applications

P Joshi, PR Riley, W Denning, S Shukla… - Journal of Materials …, 2022 - pubs.rsc.org
Medical grade polyethylene-based skeletal implants exhibit osteo-disintegration, erosion,
and modest hemocompatibility. Herein, we report on the fabrication of highly adherent …

Effect of hydrophilic groups on the bioactivity of antimicrobial polymers

P Pham, S Oliver, EHH Wong, C Boyer - Polymer Chemistry, 2021 - pubs.rsc.org
Antimicrobial polymers have recently been investigated as potential treatments to combat
multidrug-resistant pathogens. A typical antimicrobial polymer consists of cationic groups …

Biodegradable polymers and polymer composites with antibacterial properties

A Smola-Dmochowska, K Lewicka, A Macyk… - International journal of …, 2023 - mdpi.com
Antibiotic resistance is one of the greatest threats to global health and food security today. It
becomes increasingly difficult to treat infectious disorders because antibiotics, even the …