Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?
RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives
K Peng, BB Liang, W Liu, ZW Mao - Coordination Chemistry Reviews, 2021 - Elsevier
Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …
intensive works have been conducted to explore more platinum coordination complexes as …
Simultaneous Photoactivation of cGAS‐STING Pathway and Pyroptosis by Platinum (II) Triphenylamine Complexes for Cancer Immunotherapy
YY Ling, XY **a, L Hao, WJ Wang, H Zhang… - Angewandte …, 2022 - Wiley Online Library
Activation of the cyclic GMP‐AMP synthase‐stimulator of the interferon gene (cGAS‐STING)
pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis …
pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis …
Recent advances in the synthesis, stability, and activation of platinum (IV) anticancer prodrugs
Platinum-based anticancer drugs have been widely applied in clinical settings for more than
40 years. The remarkable breakthroughs that have come from the use of these complexes in …
40 years. The remarkable breakthroughs that have come from the use of these complexes in …
A photocaged, water-oxidizing, and nucleolus-targeted Pt (IV) complex with a distinct anticancer mechanism
Targeted anticancer prodrugs that can be controllably activated are highly desired for
personalized precision medicine in cancer therapy. Such prodrugs with unique action …
personalized precision medicine in cancer therapy. Such prodrugs with unique action …
Fighting against drug‐resistant tumors using a dual‐responsive Pt (IV)/Ru (II) bimetallic polymer
Drug resistance is a major problem in cancer treatment. Herein, the design of a dual‐
responsive Pt (IV)/Ru (II) bimetallic polymer (PolyPt/Ru) to treat cisplatin‐resistant tumors in …
responsive Pt (IV)/Ru (II) bimetallic polymer (PolyPt/Ru) to treat cisplatin‐resistant tumors in …
Advances in multiple stimuli-responsive drug-delivery systems for cancer therapy
R Jia, L Teng, L Gao, T Su, L Fu, Z Qiu… - International journal of …, 2021 - Taylor & Francis
Nanomedicines afford unique advantages in therapeutic intervention against tumors.
However, conventional nanomedicines have failed to achieve the desired effect against …
However, conventional nanomedicines have failed to achieve the desired effect against …
Platinum coordination compounds with potent anticancer activity
Many international researchers have strived to understand the mechanism of action or
improve the efficacy of inorganic coordination compounds that have been identified to …
improve the efficacy of inorganic coordination compounds that have been identified to …
Platinum (IV) antitumor complexes and their nano-drug delivery
C Jia, GB Deacon, Y Zhang, C Gao - Coordination Chemistry Reviews, 2021 - Elsevier
Platinum-based anticancer drugs dominate the chemotherapy field for several cancers, but
problems such as systemic toxicity and acquired resistance for some primary tumors hamper …
problems such as systemic toxicity and acquired resistance for some primary tumors hamper …
Bimetallic nanoplatforms for prostate cancer treatment by interfering cellular communication
S Zhang, X Ji, Z Liu, Z **e, Y Wang… - Journal of the …, 2024 - ACS Publications
Cellular communication mediated by messenger molecules plays an important role in the
progression of cancer. Herein, pH-sensitive zeolitic imidazolate framework-8 (ZIF-8) loaded …
progression of cancer. Herein, pH-sensitive zeolitic imidazolate framework-8 (ZIF-8) loaded …