Capsaicin may have important potential for promoting vascular and metabolic health
MF McCarty, JJ DiNicolantonio, JH O'Keefe - Open Heart, 2015 - openheart.bmj.com
Capsaicin, the phytochemical responsible for the spiciness of peppers, has the potential to
modulate metabolism via activation of transient receptor potential vanilloid 1 (TRPV1) …
modulate metabolism via activation of transient receptor potential vanilloid 1 (TRPV1) …
TRPV1 expressed throughout the arterial circulation regulates vasoconstriction and blood pressure
Key points The functional roles of the capsaicin receptor, TRPV1, outside of sensory nerves
are unclear. We mapped TRPV1 in the mouse circulation, revealing extensive expression in …
are unclear. We mapped TRPV1 in the mouse circulation, revealing extensive expression in …
The vanilloid (capsaicin) receptor TRPV1 in blood pressure regulation: a novel therapeutic target in hypertension?
A Szallasi - International journal of molecular sciences, 2023 - mdpi.com
Today's sedentary lifestyle with excess food and little exercise increases the number of
people with hypertension, a major risk factor for stroke. New knowledge of treatments in this …
people with hypertension, a major risk factor for stroke. New knowledge of treatments in this …
[HTML][HTML] Capsaicin-sensitive sensory nerves exert complex regulatory functions in the serum-transfer mouse model of autoimmune arthritis
Abstract Objective The K/BxN serum-transfer arthritis is a widely-used translational mouse
model of rheumatoid arthritis, in which the immunological components have thoroughly …
model of rheumatoid arthritis, in which the immunological components have thoroughly …
Pigment epithelium-derived factor mitigates inflammation and oxidative stress in retinal pericytes exposed to oxidized low-density lipoprotein
Transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) receptors expressed
predominantly in sensory nerves are activated by inflammatory stimuli and mediate …
predominantly in sensory nerves are activated by inflammatory stimuli and mediate …
TRPV1 in arteries enables a rapid myogenic tone
Arterioles maintain blow flow by adjusting their diameter in response to changes in local
blood pressure. In this process called the myogenic response, a vascular smooth muscle …
blood pressure. In this process called the myogenic response, a vascular smooth muscle …
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men …
VEL de Moura e Silva, JM Cholewa, R Jäger… - Journal of the …, 2021 - Springer
Background Acute capsaicinoid and capsinoid supplementation has endurance and
resistance exercise benefits; however, if these short-term performance benefits translate into …
resistance exercise benefits; however, if these short-term performance benefits translate into …
Nano-sized carriers for capsaicinoids with topic analgesic and anti-inflammatory effects
Capsaicinoids confer the pungency in chili peppers and are proven to contain many
beneficial traits, among them analgesic and anti-inflammatory properties. Capsaicinoids …
beneficial traits, among them analgesic and anti-inflammatory properties. Capsaicinoids …
Activation of the cation channel TRPM3 in perivascular nerves induces vasodilation of resistance arteries
L Alonso-Carbajo, YA Alpizar, JB Startek… - Journal of Molecular and …, 2019 - Elsevier
Abstract The Transient Receptor Potential Melastatin 3 (TRPM3) is a Ca 2+-permeable non-
selective cation channel activated by the neurosteroid pregnenolone sulfate (PS). This …
selective cation channel activated by the neurosteroid pregnenolone sulfate (PS). This …
The emerging role of TRPV1 in airway inflammation
JH Kim - Allergy, Asthma & Immunology Research, 2018 - synapse.koreamed.org
Volume 10, Number 3, May 2018 188 http://e-aair. org tion among different tissues after
antagonist stimulation is difficult; however, determining the similarities and differences …
antagonist stimulation is difficult; however, determining the similarities and differences …