Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …

N, O-containing five-membered heterocycles especially oxazole and isoxazole, have widely
been found in many natural products and drugs with relevant medicinal and pharmaceutical …

Cyclooxygenase-2 is a very important physiological enzyme playing key roles in various
biological functions especially in the mechanism of pain and inflammation, among other …

The presence of benzoxazole moiety in most of the heterocyclic compounds is well reported.
The present literature review mainly highlights the novel synthetic transformation and …

Piperazine, a nitrogen-containing heterocyclic has acquired an inimitable position in
medicinal chemistry because of its versatile structure, which has fascinated researchers to …

Oxazole contain an oxygen atom and a pyridine type nitrogen atom at the 1 and 3 positions
of the ring and like pyridine, oxazole are weekly basic substances. Oxazole be considered …

In search of novel biologically potent compounds, some new oxazolyl pyrimidines (7a-g)
have been prepared in the current investigation. All new compounds were characterized …

In continuation of the synthesis of potent quinoline based anticancer agents, a series of
novel quinoline‐1, 3‐oxazole hybrids 15 a‐l were synthesized by the condensation reaction …

This review stretches insight about the advancement (2011–2021) of synthesized non-
heterocyclic, heterocyclic and natural occurring cyclic molecules for inflammation. While …

Aim: Over the last few decades, therapeutic needs have led to a search for safer COX-2
inhibitors with potential anti-inflammatory and analgesic activity. Materials & methods: A new …