The evolution of human genetic and phenotypic variation in Africa

MC Campbell, SA Tishkoff - Current biology, 2010 - cell.com
Africa is the birthplace of modern humans, and is the source of the geographic expansion of
ancestral populations into other regions of the world. Indigenous Africans are characterized …

Genetic variation and adaptation in Africa: implications for human evolution and disease

F Gomez, J Hirbo, SA Tishkoff - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Because modern humans originated in Africa and have adapted to diverse environments,
African populations have high levels of genetic and phenotypic diversity. Thus, genomic …

Inferring human population size and separation history from multiple genome sequences

S Schiffels, R Durbin - Nature genetics, 2014 - nature.com
The availability of complete human genome sequences from populations across the world
has given rise to new population genetic inference methods that explicitly model ancestral …

Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America

E Patin, M Lopez, R Grollemund, P Verdu, C Harmant… - Science, 2017 - science.org
Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-
speaking populations remains largely unexplored. We generated genomic data for 1318 …

Ancient West African foragers in the context of African population history

M Lipson, I Ribot, S Mallick, N Rohland, I Olalde… - Nature, 2020 - nature.com
Our knowledge of ancient human population structure in sub-Saharan Africa, particularly
prior to the advent of food production, remains limited. Here we report genome-wide DNA …

[BOK][B] Human evolutionary genetics: origins, peoples and disease

M Jobling, C Tyler-Smith - 2019 - taylorfrancis.com
Human Evolutionary Genetics is a groundbreaking text which for the first time brings
together molecular genetics and genomics to the study of the origins and movements of …

Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

BM Henn, CR Gignoux, M Jobin… - Proceedings of the …, 2011 - National Acad Sciences
Africa is inferred to be the continent of origin for all modern human populations, but the
details of human prehistory and evolution in Africa remain largely obscure owing to the …

[HTML][HTML] Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers

J Lachance, B Vernot, CC Elbers, B Ferwerda… - Cell, 2012 - cell.com
To reconstruct modern human evolutionary history and identify loci that have shaped hunter-
gatherer adaptation, we sequenced the whole genomes of five individuals in each of three …

Complete Khoisan and Bantu genomes from southern Africa

SC Schuster, W Miller, A Ratan, LP Tomsho, B Giardine… - Nature, 2010 - nature.com
The genetic structure of the indigenous hunter-gatherer peoples of southern Africa, the
oldest known lineage of modern human, is important for understanding human diversity …

The Y-chromosome tree bursts into leaf: 13,000 high-confidence SNPs covering the majority of known clades

P Hallast, C Batini, D Zadik… - Molecular biology …, 2015 - academic.oup.com
Many studies of human populations have used the male-specific region of the Y
chromosome (MSY) as a marker, but MSY sequence variants have traditionally been subject …