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Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering
Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …
Peptide fibrillization
IW Hamley - Angewandte Chemie International Edition, 2007 - Wiley Online Library
The fibrillization of peptides is relevant to many diseases based on the deposition of
amyloids. The formation of fibrils is being intensively studied, especially in terms of …
amyloids. The formation of fibrils is being intensively studied, especially in terms of …
Integrating Computation, Experiment, and Machine Learning in the Design of Peptide‐Based Supramolecular Materials and Systems
M Ramakrishnan, A van Teijlingen… - Angewandte Chemie …, 2023 - Wiley Online Library
Interest in peptide‐based supramolecular materials has grown extensively since the 1980s
and the application of computational methods has paralleled this. These methods contribute …
and the application of computational methods has paralleled this. These methods contribute …
Self-assembling peptides: From design to biomedical applications
S La Manna, C Di Natale, V Onesto… - International journal of …, 2021 - mdpi.com
Self-assembling peptides could be considered a novel class of agents able to harvest an
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …
array of micro/nanostructures that are highly attractive in the biomedical field. By modifying …
Short to ultrashort peptide-based hydrogels as a platform for biomedical applications
Short peptides have attracted significant attention from researchers in the past few years due
to their easy design, synthesis and characterization, diverse functionalisation possibilities …
to their easy design, synthesis and characterization, diverse functionalisation possibilities …
Peptide hydrogels–versatile matrices for 3D cell culture in cancer medicine
P Worthington, DJ Pochan, SA Langhans - Frontiers in oncology, 2015 - frontiersin.org
Traditional two-dimensional (2D) cell culture systems have contributed tremendously to our
understanding of cancer biology but have significant limitations in mimicking in vivo …
understanding of cancer biology but have significant limitations in mimicking in vivo …
Peptide sequence determines structural sensitivity to supramolecular polymerization pathways and bioactivity
Pathways in supramolecular polymerization traverse different regions of the system's energy
landscape, affecting not only their architectures and internal structure but also their …
landscape, affecting not only their architectures and internal structure but also their …
Revisiting thioflavin T (ThT) fluorescence as a marker of protein fibrillation–The prominent role of electrostatic interactions
Thioflavin T (ThT), a benzothiazole-based fluorophore, is a prominent dye widely employed
for monitoring amyloid fibril assembly. Despite the near-universal presumption that ThT …
for monitoring amyloid fibril assembly. Despite the near-universal presumption that ThT …
Self-assembly and gelation properties of α-helix versus β-sheet forming peptides
We have investigated the self-assembly and gelation properties of a set of four octa-
peptides: AEAEAKAK, AEAKAEAK, FEFEFKFK and FEFKFEFK. The phenylalanine based …
peptides: AEAEAKAK, AEAKAEAK, FEFEFKFK and FEFKFEFK. The phenylalanine based …
Self-assembly of ionic-complementary peptides: a physicochemical viewpoint
P Chen - Colloids and Surfaces A: Physicochemical and …, 2005 - Elsevier
A major focus in the current development in nanotechnology and biotechnology is to find
suitable molecular materials that are amenable to engineering design. Self-assembling …
suitable molecular materials that are amenable to engineering design. Self-assembling …