Control of long-term plasticity by glutamate transporters

S Valtcheva, L Venance - Frontiers in synaptic neuroscience, 2019 - frontiersin.org
Activity-dependent long-term changes in synaptic strength constitute key elements for
learning and memory formation. Long-term plasticity can be induced in vivo and ex vivo by …

Alterations in the Nervous System and Gut Microbiota after β-Hemolytic Streptococcus Group A Infection—Characteristics and Diagnostic Criteria of PANDAS …

J Baj, E Sitarz, A Forma, K Wróblewska… - International journal of …, 2020 - mdpi.com
The objective of this paper is to review and summarize conclusions from the available
literature regarding Pediatric Autoimmune Neuropsychiatric Disorders Associated with …

[HTML][HTML] Pathway-specific alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior

JM Malgady, A Baez, ZB Hobel, K Jimenez, J Goldfried… - Cell reports, 2023 - cell.com
Deletion of the obsessive-compulsive disorder (OCD)-associated gene SAP90/PSD-95-
associated protein 3 (Sapap3), which encodes a postsynaptic anchoring protein at …

Regulation of glutamate, GABA and dopamine transporter uptake, surface mobility and expression

RM Ryan, SL Ingram, A Scimemi - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Neurotransmitter transporters limit spillover between synapses and maintain the
extracellular neurotransmitter concentration at low yet physiologically meaningful levels …

Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression

C Delgado-Acevedo, SF Estay, AK Radke… - …, 2019 - nature.com
Obsessive-compulsive disorder (OCD) is a severe, chronic neuropsychiatric disorder with a
strong genetic component. The SLC1A1 gene encoding the neuronal glutamate transporter …

Forebrain EAAT3 overexpression increases susceptibility to amphetamine-induced repetitive behaviors

JM Kopelman, MO Chohan, AI Hsu, EA Yttri… - Eneuro, 2024 - eneuro.org
Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder characterized by
intrusive obsessive thoughts and compulsive behaviors. Multiple studies have shown the …

Cannabis improves obsessive-compulsive disorder—Case report and review of the literature

N Szejko, C Fremer, KR Müller-Vahl - Frontiers in Psychiatry, 2020 - frontiersin.org
Although several lines of evidence support the hypothesis of a dysregulation of
serotoninergic neurotransmission in the pathophysiology of obsessive-compulsive disorder …

Animal models for OCD research

BL Chamberlain, SE Ahmari - The Neurobiology and Treatment of OCD …, 2021 - Springer
OCD has lagged behind other psychiatric illnesses in the identification of molecular
treatment targets, due in part to a lack of significant findings in genome-wide association …

Glutamate transporters: Gene expression regulation and signaling properties

TN Olivares-Bañuelos, D Chí-Castañeda, A Ortega - Neuropharmacology, 2019 - Elsevier
Glutamate is the major excitatory neurotransmitter in the vertebrate central nervous system.
During synaptic activity, glutamate is released and binds to specific membrane receptors …

Methamphetamine-induced apoptosis in glial cells examined under marker-free imaging modalities

LY D'Brant, H Desta, TC Khoo… - … of biomedical optics, 2019 - spiedigitallibrary.org
We used phase microscopy and Raman spectroscopic measurements to assess the
response of in vitro rat C6 glial cells following methamphetamine treatment in real time …