The most common form of genetic variation, single nucleotide polymorphisms or SNPs, can
affect the way an individual responds to the environment and modify disease risk. Although …

Abstract The Animal Transcription Factor DataBase (AnimalTFDB) is a resource aimed to
provide the most comprehensive and accurate information for animal transcription factors …

Single nucleotide polymorphisms (SNPs) in the human genome are DNA sequence
variations that can alter an individual's response to environmental exposure. SNPs in gene …

Sequence variants in gene regulatory regions alter gene expression and contribute to
phenotypes of individual cells and the whole organism, including disease susceptibility and …

CKLF-like MARVEL transmembrane domain-containing 2 (CMTM2) plays an important role
in animal reproduction, and abnormal CMTM2 expression leads to spermatogenesis …

Macrophages represent the first line of anti-pathogen defense-they encounter invading
pathogens to perform the phagocytic activity, to deliver the plethora of pro-and anti …

Tryptophan is metabolized primarily via the kynurenine pathway (KP), which involves
several enzymes, including indoleamine 2, 3-dioxygenase, tryptophan 2, 3 dioxygenase …

The hypothesis was tested that sequence diversity in breast cancer resistance protein
(BCRP)'s cis-regulatory region is a significant determinant of BCRP expression. The BCRP …

The use of biomedical SNP markers of diseases can improve effectiveness of treatment.
Genoty** of patients with subsequent searching for SNPs more frequent than in norm is …

A vast amount of SNPs derived from genome-wide association studies are represented by
non-coding ones, therefore exacerbating the need for effective identification of regulatory …