During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Synapses are highly plastic and are modified by changes in patterns of neural activity or
sensory experience. Plasticity of cortical excitatory synapses is thought to be important for …

Ionic currents and the network-driven patterns they generate differ in immature and adult
neurons: The develo** brain is not a “small adult brain.” One of the most investigated …

Prolactin is a protein hormone of the anterior pituitary gland that was originally named for its
ability to promote lactation in response to the suckling stimulus of hungry young mammals …

In the immature brain, GABA (γ-aminobutyric acid) is excitatory, and GABA-releasing
synapses are formed before glutamatergic contacts in a wide range of species and …

GABA is the major inhibitory neurotransmitter that counterbalances excitation in the mature
brain. The inhibitory action of GABA relies on the inflow of chloride ions (Cl−), which …

From early embryonic development to adulthood, GABA release participates in the
construction of the mammalian cerebral cortex. The maturation of GABAergic …

Develo** networks follow common rules to shift from silent cells to coactive networks that
operate via thousands of synapses. This review deals with some of these rules and in …

Adult neurogenesis, the birth and integration of new neurons from adult neural stem cells, is
a striking form of structural plasticity and highlights the regenerative capacity of the adult …