Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Progress in nanomaterial-based synergistic photothermal-enhanced chemodynamic therapy in combating bacterial infections

P Manivasagan, T Thambi, A Joe, HW Han… - Progress in Materials …, 2024 - Elsevier
The prevalence of multidrug-resistant (MDR) bacterial infections has emerged as a serious
threat to clinical treatment and global human health, and has become one of the most …

Coordination-driven self-assembly strategy-activated Cu single-atom nanozymes for catalytic tumor-specific therapy

J Zhou, D Xu, G Tian, Q He, X Zhang… - Journal of the …, 2023 - ACS Publications
How to optimize the enzyme-like catalytic activity of nanozymes to improve their applicability
has become a great challenge. Herein, we present an l-cysteine (l-Cys) coordination-driven …

Piezo‐Augmented and photocatalytic nanozyme integrated microneedles for antibacterial and anti‐inflammatory combination therapy

S Shi, Y Jiang, Y Yu, M Liang, Q Bai… - Advanced Functional …, 2023 - Wiley Online Library
Wound infection is arguably the most common, and potentially the most devastating,
complication of the wound healing process. The ideal treatment strategy has to eliminate …

Recent advances in photo‐responsive carbon dots for tumor therapy

H Zhang, Y Liu, S Qu - Responsive Materials, 2024 - Wiley Online Library
The precision treatment of tumors with minimal side effects is associated with improved
human health and quality of life. In recent years, phototherapy has attracted significant …

Accelerating Ce3+/Ce4+ conversion in CeO2 via Mn do** to endow scaffolds with chemodynamic therapy properties

C Shuai, K Wang, S Peng, J Zan, J **ao, S Hu… - Surfaces and …, 2024 - Elsevier
CeO 2 nanozymes have garnered significant attention in chemodynamic therapy due to their
peroxidase-like activity and ability to deplete glutathione. However, their catalytic efficiency …

A stable open-shell conjugated diradical polymer with ultra-high photothermal conversion efficiency for NIR-II photo-immunotherapy of metastatic tumor

Y Gao, Y Liu, X Li, H Wang, Y Yang, Y Luo, Y Wan… - Nano-Micro Letters, 2024 - Springer
Massive efforts have been concentrated on the advance of eminent near-infrared (NIR)
photothermal materials (PTMs) in the NIR-II window (1000–1700 nm), especially organic …

Activity regulating strategies of nanozymes for biomedical applications

X Ding, Z Zhao, Y Zhang, M Duan, C Liu, Y Xu - Small, 2023 - Wiley Online Library
On accounts of the advantages of inherent high stability, ease of preparation and superior
catalytic activities, nanozymes have attracted tremendous potential in diverse biomedical …

Plasmonic Supramolecular Nanozyme‐Based Bio‐Cockleburs for Synergistic Therapy of Infected Diabetic Wounds

X Wang, X Qin, Y Liu, Y Fang, H Meng… - Advanced …, 2024 - Wiley Online Library
Diabetic wounds are a major devastating complication of diabetes due to hyperglycemia,
bacterial invasion, and persistent inflammation, and the current antibiotic treatments can …

Metal‐Based Nanozymes with Multienzyme‐Like Activities as Therapeutic Candidates: Applications, Mechanisms, and Optimization Strategy

D Li, D Dai, G **ong, S Lan, C Zhang - Small, 2023 - Wiley Online Library
Most nanozymes in development for medical applications only exhibit single‐enzyme‐like
activity, and are thus limited by insufficient catalytic activity and dysfunctionality in complex …