Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

The Paneth cell: the curator and defender of the immature small intestine

SR Lueschow, SJ McElroy - Frontiers in immunology, 2020 - frontiersin.org
Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef
Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their …

[HTML][HTML] Berberine: A review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

Survey of transfusion practices in preterm infants in Europe

A Scrivens, NJ Reibel, L Heeger, S Stanworth… - Archives of Disease in …, 2023 - fn.bmj.com
Background Preterm infants commonly receive red blood cell (RBC), platelet and fresh
frozen plasma (FFP) transfusions. The aim of this Neonatal Transfusion Network survey was …

Models of necrotizing enterocolitis

CM Lopez, MES Sampah, JW Duess, A Ishiyama… - Seminars in …, 2023 - Elsevier
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. The mortality of patients with NEC is …

Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway

F Ma, H Hao, X Gao, Y Cai, J Zhou, P Liang, J Lv… - …, 2020 - pmc.ncbi.nlm.nih.gov
Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease affecting premature
infants. Mounting evidence supports the therapeutic effect of melatonin on NEC, although …

Timing of red blood cell transfusions and occurrence of necrotizing enterocolitis: a secondary analysis of a randomized clinical trial

AA Salas, E Gunn, WA Carlo, EF Bell, A Das… - JAMA network …, 2024 - jamanetwork.com
Importance Observational studies often report that anemia and red blood cell (RBC)
transfusions are associated with a higher risk of necrotizing enterocolitis (NEC) among …

Anemia of prematurity: how low is too low?

CC Cibulskis, A Maheshwari, R Rao… - Journal of …, 2021 - nature.com
Anemia of prematurity (AOP) is a common condition with a well-described chronology, nadir
hemoglobin levels, and timeline of recovery. However, the underlying pathophysiology and …

[HTML][HTML] Clinical dilemma involving treatments for very low-birth-weight infants and the potential risk of necrotizing enterocolitis: a narrative literature review

S Iijima - Journal of Clinical Medicine, 2023 - mdpi.com
Necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency with substantial
morbidity and mortality risks, especially for very low-birth-weight (VLBW) infants, and unclear …

The association of severe anemia, red blood cell transfusion and necrotizing enterocolitis in neonates

J Song, H Dong, F Xu, Y Wang, W Li, Z Jue, L Wei… - PLoS …, 2021 - journals.plos.org
Background The relationship between severe anemia, red blood cell transfusion and
Neonatal necrotizing enterocolitis (NEC) remains controversial. The purpose of this study …