The dopamine hypothesis of autism spectrum disorder revisited: current status and future prospects
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. Despite intensive research, its …
characterized by social deficits and stereotyped behaviors. Despite intensive research, its …
A systematic review of brainstem contributions to autism spectrum disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects one in 66
children in Canada. The contributions of changes in the cortex and cerebellum to autism …
children in Canada. The contributions of changes in the cortex and cerebellum to autism …
Pathophysiological studies of monoaminergic neurotransmission systems in valproic acid-induced model of autism spectrum disorder
HY Kuo, FC Liu - Biomedicines, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology.
The core syndromes of ASD are deficits in social communication and self-restricted interests …
The core syndromes of ASD are deficits in social communication and self-restricted interests …
Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of …
CK Finszter, R Kemecsei, G Zachar, Á Ádám… - Frontiers in …, 2024 - frontiersin.org
Gestational exposure to valproic acid (VPA) is a valid rodent model of human autism
spectrum disorder (ASD). VPA treatment is known to bring about specific behavioral deficits …
spectrum disorder (ASD). VPA treatment is known to bring about specific behavioral deficits …
Early cellular and synaptic changes in dopaminoceptive forebrain regions of juvenile mice following gestational exposure to valproate
CK Finszter, R Kemecsei, G Zachar… - Frontiers in …, 2023 - frontiersin.org
Gestational exposure of mice to valproic acid (VPA) is one currently used experimental
model for the investigation of typical failure symptoms associated with autism spectrum …
model for the investigation of typical failure symptoms associated with autism spectrum …
Neuroprotective efficacy of fisetin against VPA-induced autistic neurobehavioral alterations by targeting dysregulated redox homeostasis
S Mehra, AU Ahsan, M Sharma, M Budhwar… - Journal of Molecular …, 2023 - Springer
Autism is a neurodevelopmental condition, and it's associated pathophysiology, viz.,
oxidative stress and altered cellular homeostasis, has been extensively intertwined with …
oxidative stress and altered cellular homeostasis, has been extensively intertwined with …
The Cerebellum–Ventral Tegmental Area Microcircuit and Its Implications for Autism Spectrum Disorder: A Narrative Review
P Zhou, S Peng, S Wen, Q Lan, Y Zhuang… - Neuropsychiatric …, 2024 - Taylor & Francis
The cerebellum has long been implicated in the etiopathogenesis of autism spectrum
disorder (ASD), and emerging evidence suggests a significant contribution by reciprocal …
disorder (ASD), and emerging evidence suggests a significant contribution by reciprocal …
Prenatal Valproic Acid Induces Autistic‐Like Behaviors in Rats via Dopaminergic Modulation in Nigrostriatal and Mesocorticolimbic Pathways
LC Cezar, CCN da Fonseca, MO Klein… - Journal of …, 2025 - Wiley Online Library
Autism spectrum disorder (ASD) is a complex developmental disorder characterized by
several behavioral impairments, especially in socialization, communication, and the …
several behavioral impairments, especially in socialization, communication, and the …
Sex differences in autism‐like behavior and dopaminergic neurons in substantia nigra of juvenile mice prenatally exposed to valproate
D Zarate‐Lopez, AP Garzón‐Partida… - Developmental …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is characterized by deficits in social interaction and
communication and repetitive and restricted behaviors. Sex dimorphism in the brain …
communication and repetitive and restricted behaviors. Sex dimorphism in the brain …
Embryonic valproate exposure alters mesencephalic dopaminergic neurons distribution and septal dopaminergic gene expression in domestic chicks
In recent years, the role of the dopaminergic system in the regulation of social behavior is
being progressively outlined, and dysfunctions of the dopaminergic system are increasingly …
being progressively outlined, and dysfunctions of the dopaminergic system are increasingly …