The management of diabetic retinopathy (DR) has evolved considerably over the past
decade, with the availability of new technologies (diagnostic and therapeutic). As such, the …

Progress in preventing atherosclerotic coronary artery disease (CAD) has been stalled by
the epidemic of type 2 diabetes. Further advances in this area demand a thorough …

Several studies have reported a strong association between high plasma level of
trimethylamine N-oxide (TMAO) and atherosclerosis development. However, the exact …

The prevalence of diabetes has dramatically increased worldwide due to the vast increase
in the obesity rate. Diabetic nephropathy is one of the major complications of type 1 and type …

The effects of intermittent and constant high glucose in the formation of nitrotyrosine and 8-
hydroxydeoxyguanosine (markers of oxidative stress), as well as the possible linkage …

Diabetes mellitus is associated with an increased risk of cardiovascular disease, even in the
presence of intensive glycemic control. Substantial clinical and experimental evidence …

Introduction: Diabetic nephropathy (DN) is the leading cause of chronic kidney disease
(CKD) and end-stage renal disease (ESRD). Beyond the new anti-diabetic drugs that …

As a first-line treatment for diabetes, the insulin-sensitizing biguanide, metformin, regulates
glucose levels and positively affects cardiovascular function in patients with diabetes and …

In this study the effects of stable and intermittent high glucose concentrations on ICAM-1,
VCAM-1 and E-selectin production, PKC activity and PKCβI, βII and δ isoforms expression in …

Diabetic nephropathy is a leading cause of end-stage renal failure and is a growing concern
given the increasing incidence of type 2 diabetes. Diabetic nephropathy is associated with …