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Immunopathology of herpes simplex virus‐associated neuroinflammation: Unveiling the mysteries
The immunopathology of herpes simplex virus (HSV)‐associated neuroinflammation is a
captivating and intricate field of study within the scientific community. HSV, renowned for its …
captivating and intricate field of study within the scientific community. HSV, renowned for its …
Small animal models to study herpes simplex virus infections
Herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) are two of the
most prevalent human viruses worldwide. They are known to cause a variety of diseases …
most prevalent human viruses worldwide. They are known to cause a variety of diseases …
High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from …
Background Cross-reactive SARS-CoV-2-specific memory CD4+ and CD8+ T cells are
present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However …
present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However …
[HTML][HTML] Immune response to herpes simplex virus infection and vaccine development
Herpes simplex virus (HSV) infections are among the most common viral infections and
usually last for a lifetime. The virus can potentially be controlled with vaccines since humans …
usually last for a lifetime. The virus can potentially be controlled with vaccines since humans …
[HTML][HTML] The quest for immunity: exploring human herpesviruses as vaccine vectors
Herpesviruses are large DNA viruses that have long been used as powerful gene therapy
tools. In recent years, the ability of herpesviruses to stimulate both innate and adaptive …
tools. In recent years, the ability of herpesviruses to stimulate both innate and adaptive …
Current vaccine approaches and emerging strategies against herpes simplex virus (HSV)
VN Wijesinghe, IA Farouk, NZ Zabidi… - Expert Review of …, 2021 - Taylor & Francis
Introduction Vaccine development for the disease caused by the herpes simplex virus (HSV)
has been challenging over the years and is always in dire need of novel approaches for …
has been challenging over the years and is always in dire need of novel approaches for …
The impact of cross-reactive immunity on the emergence of SARS-CoV-2 variants
Introduction A key feature of the COVID-19 pandemic has been the emergence of SARS-
CoV-2 variants with different transmission characteristics. However, when a novel variant …
CoV-2 variants with different transmission characteristics. However, when a novel variant …
Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces …
Chronic viruses such as herpes simplex virus 1 (HSV-1) evade the hosts' immune system by
inducing the exhaustion of antiviral T cells. In the present study, we found that exhausted …
inducing the exhaustion of antiviral T cells. In the present study, we found that exhausted …
Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local …
Following acute herpes simplex virus type 2 (HSV-2) infection, the virus undergoes an
asymptomatic latent infection of sensory neurons of dorsal root ganglia (DRG). Chemical …
asymptomatic latent infection of sensory neurons of dorsal root ganglia (DRG). Chemical …
An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a …
M Wan, X Yang, J Sun, X Ding, Z Chen, W Su, L Cai… - Viruses, 2023 - mdpi.com
Genital herpes (GH) has become one of the most common sexually transmitted diseases
worldwide, and it is spreading rapidly in develo** countries. Approximately 90% of GH …
worldwide, and it is spreading rapidly in develo** countries. Approximately 90% of GH …