[HTML][HTML] Physiology and pathophysiology of carnosine

AA Boldyrev, G Aldini, W Derave - Physiological reviews, 2013 - journals.physiology.org
Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

The 'critical power'concept: applications to sports performance with a focus on intermittent high-intensity exercise

AM Jones, A Vanhatalo - Sports Medicine, 2017 - Springer
The curvilinear relationship between power output and the time for which it can be sustained
is a fundamental and well-known feature of high-intensity exercise performance. This …

Can high-intensity interval training promote skeletal muscle anabolism?

MJ Callahan, EB Parr, JA Hawley, DM Camera - Sports Medicine, 2021 - Springer
Exercise training in combination with optimal nutritional support is an effective strategy to
maintain or increase skeletal muscle mass. A single bout of resistance exercise undertaken …

Nutritional strategies to modulate intracellular and extracellular buffering capacity during high-intensity exercise

AH Lancha Junior, V de Salles Painelli, B Saunders… - Sports medicine, 2015 - Springer
Intramuscular acidosis is a contributing factor to fatigue during high-intensity exercise. Many
nutritional strategies aiming to increase intra-and extracellular buffering capacity have been …

Carnosine, small but mighty—prospect of use as functional ingredient for functional food formulation

I Jukić, N Kolobarić, A Stupin, A Matić, N Kozina… - Antioxidants, 2021 - mdpi.com
Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found
in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is …

Carnosine: from exercise performance to health

C Sale, GG Artioli, B Gualano, B Saunders, RM Hobson… - Amino acids, 2013 - Springer
Carnosine was first discovered in skeletal muscle, where its concentration is higher than in
any other tissue. This, along with an understanding of its role as an intracellular pH buffer …

Important considerations for protein analyses using antibody based techniques: down‐sizing Western blotting up‐sizes outcomes

RM Murphy, GD Lamb - The Journal of physiology, 2013 - Wiley Online Library
Western blotting has been used for protein analyses in a wide range of tissue samples for>
30 years. Fundamental to Western blotting success are a number of important …

Beta-alanine supplementation, muscle carnosine and exercise performance

L Blancquaert, I Everaert, W Derave - Current Opinion in Clinical …, 2015 - journals.lww.com
On the basis of the millimolar presence of carnosine in mammalian muscles, it must play a
critical role in skeletal muscle physiology. The recent number of studies shows that this is …

Effects of β-alanine supplementation and intramuscular carnosine content on exercise performance and health

AN Varanoske, JR Stout, JR Hoffman - Nutrition and enhanced sports …, 2019 - Elsevier
Abstract β-Alanine is a nonproteogenic amino acid that combines with histidine to form a
dipeptide molecule known as carnosine. Carnosine is an H+ buffer that is especially useful …

Effects of dietary supplements on adaptations to endurance training

JA Rothschild, DJ Bishop - Sports Medicine, 2020 - Springer
Endurance training leads to a variety of adaptations at the cellular and systemic levels that
serve to minimise disruptions in whole-body homeostasis caused by exercise. These …