[HTML][HTML] Review and perspective on sleep-disordered breathing research and translation to clinics

H Korkalainen, S Kainulainen, AS Islind… - Sleep Medicine …, 2024 - Elsevier
Sleep-disordered breathing, ranging from habitual snoring to severe obstructive sleep
apnea, is a prevalent public health issue. Despite rising interest in sleep and awareness of …

[HTML][HTML] Multi-night measurement for diagnosis and simplified monitoring of obstructive sleep apnoea

B Lechat, H Scott, J Manners, R Adams, S Proctor… - Sleep Medicine …, 2023 - Elsevier
Substantial night-to-night variability in obstructive sleep apnoea (OSA) severity has raised
misdiagnosis and misdirected treatment concerns with the current prevailing single-night …

Sleep apnea physiological burdens and cardiovascular morbidity and mortality

G Labarca, D Vena, WH Hu, N Esmaeili… - American Journal of …, 2023 - atsjournals.org
Rationale: Obstructive sleep apnea is characterized by frequent reductions in ventilation,
leading to oxygen desaturations and/or arousals. Objectives: In this study, association of …

Within-night repeatability and long-term consistency of sleep apnea endotypes: the Multi-Ethnic Study of Atherosclerosis and Osteoporotic Fractures in Men Study

RM Alex, T Sofer, A Azarbarzin, D Vena, LK Gell… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Obstructive sleep apnea (OSA) is characterized by multiple
“endotypic traits,” including pharyngeal collapsibility, muscle compensation, loop gain, and …

Snoring: a source of noise pollution and sleep apnea predictor

M Sowho, F Sgambati, M Guzman, H Schneider… - Sleep, 2020 - academic.oup.com
Snoring is a highly prevalent condition associated with obstructive sleep apnea (OSA) and
sleep disturbance in bed partners. Objective measurements of snoring in the community …

Neural ventilatory drive decline as a predominant mechanism of obstructive sleep apnoea events

LK Gell, D Vena, RM Alex, A Azarbarzin, N Calianese… - Thorax, 2022 - thorax.bmj.com
Background In the classic model of obstructive sleep apnoea (OSA), respiratory events
occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory …

Predicting sleep apnea responses to oral appliance therapy using polysomnographic airflow

D Vena, A Azarbarzin, M Marques, S Op de Beeck… - Sleep, 2020 - academic.oup.com
Abstract Study Objectives Oral appliance therapy is an increasingly common option for
treating obstructive sleep apnea (OSA) in patients who are intolerant to continuous positive …

Research priorities for patients with heart failure and central sleep apnea. An official American Thoracic Society research statement

JE Orr, I Ayappa, DJ Eckert, JL Feldman… - American Journal of …, 2021 - atsjournals.org
Background: Central sleep apnea (CSA) is common among patients with heart failure and
has been strongly linked to adverse outcomes. However, progress toward improving …

Pro: can physiological risk factors for obstructive sleep apnea be determined by analysis of data obtained from routine polysomnography?

SA Sands, BA Edwards - Sleep, 2023 - academic.oup.com
The following argument was prepared in response to the question without the knowledge of
the contents of the opposing argument. Obstructive sleep apnea (OSA) is a highly prevalent …

A scalable method of determining physiological endotypes of sleep apnea from a polysomnographic sleep study

E Finnsson, GH Ólafsdóttir, DL Loftsdóttir, SÆ Jónsson… - Sleep, 2021 - academic.oup.com
Sleep apnea is caused by several endophenotypic traits, namely pharyngeal collapsibility,
poor muscle compensation, ventilatory instability (high loop gain), and arousability from …