Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …

Atherosclerosis is a chronic disease characterized by the deposition of excessive
cholesterol in the arterial intima. Macrophage foam cells play a critical role in the occurrence …

Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes
attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and …

The enzymes acyl-coenzyme A (CoA): cholesterol acyltransferases (ACATs) are membrane-
bound proteins that utilize long-chain fatty acyl-CoA and cholesterol as substrates to form …

Epidemiological studies have confirmed that PM 2.5 could contribute to the development of
atherosclerosis accompanied with lipids dysregulation. However, the lipids biomarkers …

Atherosclerosis can be regarded as a chronic disease derived from the interaction between
disordered lipoproteins and an unsuitable immune response. The evolution of foam cells is …

OBJECTIVE: Triglyceride-rich lipoproteins (TGRLs) are a cardiovascular risk factor and
induce endothelial dysfunction. In the present study, we investigated the effects of post …

Recent evidence indicates that hydrogen sulfide (H2S) exerts an antiatherogenic effect, but
the mechanism is unclear. Formation of macrophage-derived foam cells is a crucial event in …

Heparan sulfate proteoglycans (HSPGs) are an important constituent of the macrophage
glycocalyx and extracellular microenvironment. To examine their role in atherogenesis, we …

Many studies have linked airborne fine particulate matter (PM2. 5) exposure to
cardiovascular diseases. We performed a time-series analysis to investigate whether the …