Regulation of the hypothalamic-pituitary-adrenocortical stress response

JP Herman, JM McKlveen, S Ghosal… - Comprehensive …, 2016 - pmc.ncbi.nlm.nih.gov
The hypothalamo-pituitary-adrenocortical (HPA axis) is required for stress adaptation.
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …

Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory

L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Stress weakens prefrontal networks: molecular insults to higher cognition

AFT Arnsten - Nature neuroscience, 2015 - nature.com
A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …

Psychosocial factors and sport injuries: meta-analyses for prediction and prevention

A Ivarsson, U Johnson, MB Andersen, U Tranaeus… - Sports medicine, 2017 - Springer
Background Several studies have suggested that psychosocial variables can increase the
risk of becoming injured during sport participation. Objectives The main objectives of these …

Disorders of compulsivity: a common bias towards learning habits

V Voon, K Derbyshire, C Rück, MA Irvine, Y Worbe… - Molecular …, 2015 - nature.com
Why do we repeat choices that we know are bad for us? Decision making is characterized
by the parallel engagement of two distinct systems, goal-directed and habitual, thought to …

A Hitchhiker's guide to functional magnetic resonance imaging

JM Soares, R Magalhães, PS Moreira… - Frontiers in …, 2016 - frontiersin.org
Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular
both with clinicians and researchers as they are capable of providing unique insights into …

Stress and cognition

C Sandi - Wiley Interdisciplinary Reviews: Cognitive Science, 2013 - Wiley Online Library
Stress can affect cognition in many ways, with the outcome (ie, facilitating or impairing)
depending on a combination of factors related to both stress and the cognitive function …

Neuropathology of stress

PJ Lucassen, J Pruessner, N Sousa, OFX Almeida… - Acta …, 2014 - Springer
Environmental challenges are part of daily life for any individual. In fact, stress appears to be
increasingly present in our modern, and demanding, industrialized society. Virtually every …

[HTML][HTML] Acute stress impairs self-control in goal-directed choice by altering multiple functional connections within the brain's decision circuits

SU Maier, AB Makwana, TA Hare - Neuron, 2015 - cell.com
Important decisions are often made under stressful circumstances that might compromise
self-regulatory behavior. Yet the neural mechanisms by which stress influences self-control …

Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression

MT Treadway, ML Waskom, DG Dillon, AJ Holmes… - Biological …, 2015 - Elsevier
Background Longitudinal studies of illness progression in patients with major depressive
disorder (MDD) indicate that the onset of subsequent depressive episodes becomes …