[PDF][PDF] Tissue engineering for articular cartilage repair—the state of the art

B Johnstone, M Alini, M Cucchiarini, GR Dodge… - Eur Cell Mater, 2013 - Citeseer
Adult articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries
or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting in …

Vibrational spectroscopy of articular cartilage

L Rieppo, J Töyräs, S Saarakkala - Applied spectroscopy reviews, 2017 - Taylor & Francis
Articular cartilage is a connective tissue that is located at the ends of long bones. Type II
collagen, proteoglycans, water, and chondrocytes are the main constituents of articular …

Transient exposure to TGF-β3 improves the functional chondrogenesis of MSC-laden hyaluronic acid hydrogels

M Kim, IE Erickson, M Choudhury, N Pleshko… - Journal of the …, 2012 - Elsevier
Tissue engineering with adult stem cells is a promising approach for the restoration of focal
defects in articular cartilage. For this, progenitor cells would ideally be delivered to (and …

Infrapatellar fat pad-derived stem cells maintain their chondrogenic capacity in disease and can be used to engineer cartilaginous grafts of clinically relevant …

Y Liu, CT Buckley, HV Almeida, KJ Mulhall… - … Engineering Part A, 2014 - liebertpub.com
A therapy for regenerating large cartilaginous lesions within the articular surface of
osteoarthritic joints remains elusive. While tissue engineering strategies such as matrix …

Fourier transform infrared imaging and infrared fiber optic probe spectroscopy identify collagen type in connective tissues

A Hanifi, H McCarthy, S Roberts, N Pleshko - PLoS One, 2013 - journals.plos.org
Hyaline cartilage and mechanically inferior fibrocartilage consisting of mixed collagen types
are frequently found together in repairing articular cartilage. The present study seeks to …

A comparison of self-assembly and hydrogel encapsulation as a means to engineer functional cartilaginous grafts using culture expanded chondrocytes

T Mesallati, CT Buckley, DJ Kelly - Tissue Engineering Part C …, 2014 - liebertpub.com
Despite an increased interest in the use of hydrogel encapsulation and cellular self-
assembly (often termed “self-aggregating” or “scaffold-free” approaches) for tissue …

Microscale strain concentrations in tissue-engineered osteochondral implants are dictated by local compositional thresholds and architecture

B Kim, TAN Kelly, HJ Jung, OS Beane… - Journal of …, 2024 - Elsevier
Tissue-engineered osteochondral implants manufactured from condensed mesenchymal
stem cell bodies have shown promise for treating focal cartilage defects. Notably, such …

Time-dependent functional maturation of scaffold-free cartilage tissue analogs

B Mohanraj, AJ Farran, RL Mauck, GR Dodge - Journal of biomechanics, 2014 - Elsevier
One of the most critical parameters in cartilage tissue engineering which influences the
clinical success of a repair therapy is the ability to match the load-bearing capacity of the …

Engineering articular cartilage‐like grafts by self‐assembly of infrapatellar fat pad‐derived stem cells

T Mesallati, CT Buckley, DJ Kelly - Biotechnology and …, 2014 - Wiley Online Library
Well documented limitations associated with primary chondrocytes for cartilage tissue
engineering applications have led to increased interest in the use of multi‐potent …

Optimization of Preculture Conditions to Maximize the In Vivo Performance of Cell-Seeded Engineered Intervertebral Discs

JT Martin, SE Gullbrand, B Mohanraj… - … Engineering Part A, 2017 - liebertpub.com
The development of engineered tissues has progressed over the past 20 years from in vitro
characterization to in vivo implementation. For musculoskeletal tissue engineering in …