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Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
[HTML][HTML] Using ncRNAs as tools in Cancer diagnosis and treatment—the way towards personalized medicine to improve patients' health
Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …
years has the complexity of the transcriptome started to be elucidated. However, its …
[HTML][HTML] Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives
P Basu, C Maier - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …
Inhibition of cancer development by natural plant polyphenols: Molecular mechanisms
A Lyubitelev, V Studitsky - International Journal of Molecular Sciences, 2023 - mdpi.com
Malignant tumors remain one of the main sources of morbidity and mortality around the
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …
Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
NCMD: Node2vec-based neural collaborative filtering for predicting miRNA-disease association
Numerous studies have reported that micro RNAs (miRNAs) play pivotal roles in disease
pathogenesis based on the deregulation of the expressions of target messenger RNAs …
pathogenesis based on the deregulation of the expressions of target messenger RNAs …
[HTML][HTML] Role of phytonutrients in nutrigenetics and nutrigenomics perspective in curing breast cancer
Breast cancer (BC) is one of the most common type of cancer and an important contributor to
female mortality. Several genes and epigenetic modifications are involved in the …
female mortality. Several genes and epigenetic modifications are involved in the …
Genistein as a regulator of signaling pathways and microRNAs in different types of cancers
Cancers are complex diseases orchestrated by a plethora of extrinsic and intrinsic factors.
Research spanning over several decades has provided better understanding of complex …
Research spanning over several decades has provided better understanding of complex …
Mechanistic evaluation of phytochemicals in breast cancer remedy: current understanding and future perspectives
Breast cancer is one of the most commonly diagnosed cancers around the globe and
accounts for a large proportion of fatalities in women. Despite the advancement in …
accounts for a large proportion of fatalities in women. Despite the advancement in …
Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells
C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …
malignancy affects today's society, the study of compounds isolated from natural sources …