The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Coacervation is a liquid–liquid phase separation that can occur in solutions of
macromolecules through self-assembly or electrostatic interactions. Recently, coacervates …

Currently, single therapeutic strategy designed for only boosting anti-inflammatory response
or angiogenesis in treating myocardial infarction (MI) has met with limited success due to …

Complex coacervation, a specific type of associative phase separation that happens when
oppositely charged macro-ions (or polyelectrolytes) are mixed, is the formation of a dense …

Although miR-327 had a protective effect on cardiomyocytes as described previously, the
potential mechanism still needs further exploration. The aim of this study was to investigate …

Following injury, tissue autonomously initiates a complex repair process, resulting in either
partial recovery or regeneration of tissue architecture and function in most organisms. Both …

Osteoarthritis (OA) is one of the most common chronic diseases, causing degenerative
changes in articular cartilage and subchondral bones. To date, there is no effective drug to …

Background Nonalcoholic steatohepatitis (NASH), a severe systemic and inflammatory
subtype of nonsalcoholic fatty liver disease, eventually develops into cirrhosis and …

Doxorubicin is a common chemotherapeutic agent in clinic, but myocardial toxicity limits its
use. Fibroblast growth factor (FGF) 10, a multifunctional paracrine growth factor, plays …

Objective Pulp regeneration with bioactive dentin-pulp complex has been a research
hotspot in recent years. Stem cell therapy provided an interest strategy to regenerate the …