Current and Future Pathways in Aspergillus Diagnosis

R Dobiáš, DA Stevens, V Havlíček - Antibiotics, 2023 - mdpi.com
Aspergillus fumigatus has been designated by the World Health Organization as a critical
priority fungal pathogen. Some commercially available diagnostics for many forms of …

[HTML][HTML] Novel treatment approach for aspergilloses by targeting germination

K Verburg, J van Neer, M Duca, H de Cock - Journal of Fungi, 2022 - mdpi.com
Germination of conidia is an essential process within the Aspergillus life cycle and plays a
major role during the infection of hosts. Conidia are able to avoid detection by the majority of …

Functional genomic and biochemical analysis reveals pleiotropic effect of Congo red on Aspergillus fumigatus

Z Liu, S Raj, N Van Rhijn, M Fraczek, JP Michel… - MBio, 2021 - journals.asm.org
Inhibition of fungal growth by Congo red (CR) has been putatively associated with specific
binding to β-1, 3-glucans, which blocks cell wall polysaccharide synthesis. In this study, we …

[HTML][HTML] The MYST Family Histone Acetyltransferase SasC Governs Diverse Biological Processes in Aspergillus fumigatus

JY Kwon, YH Choi, MW Lee, JH Yu, KS Shin - Cells, 2023 - mdpi.com
The conserved MYST proteins form the largest family of histone acetyltransferases (HATs)
that acetylate lysines within the N-terminal tails of histone, enabling active gene …

Siderophore-based noninvasive differentiation of Aspergillus fumigatus colonization and invasion in pulmonary aspergillosis

D Luptáková, RH Patil, R Dobiáš… - Microbiology …, 2023 - journals.asm.org
Germination from conidia to hyphae and hyphal propagation of Aspergillus fumigatus are
the key pathogenic steps in the development of invasive pulmonary aspergillosis (IPA). By …

Cell wall of Aspergillus fumigatus: variability and response to stress

JP Latgé - Fungal Biology, 2023 - Elsevier
The fungal cell is surrounded by a thick cell wall which obviously play an essential role in
the protection of the fungus against external aggressive environments. In spite of 50 years of …

Exploring class III cellobiose dehydrogenase: sequence analysis and optimized recombinant expression

A Giorgianni, A Zenone, L Sützl, F Csarman… - Microbial Cell …, 2024 - Springer
Background Cellobiose dehydrogenase (CDH) is an extracellular fungal oxidoreductase
with multiple functions in plant biomass degradation. Its primary function as an auxiliary …

Conidium Specific Polysaccharides in Aspergillus fumigatus

Z Liu, I Valsecchi, RA Le Meur, C Simenel, JI Guijarro… - Journal of Fungi, 2023 - mdpi.com
Earlier studies have shown that the outer layers of the conidial and mycelial cell walls of
Aspergillus fumigatus are different. In this work, we analyzed the polysaccharidome of the …

Exploring a novel genomic safe-haven site in the human pathogenic mould Aspergillus fumigatus

T Furukawa, N van Rhijn, H Chown, J Rhodes… - Fungal Genetics and …, 2022 - Elsevier
Aspergillus fumigatus is the most important airborne fungal pathogen and allergen of
humans causing high morbidity and mortality worldwide. The factors that govern …