Sex differences and the endocannabinoid system in pain
Cannabis use has been increasing in recent years, particularly among women, and one of
the most common uses of cannabis for medical purposes is pain relief. Pain conditions and …
the most common uses of cannabis for medical purposes is pain relief. Pain conditions and …
Modulation of pain by estrogens
RM Craft - Pain, 2007 - Elsevier
It has become increasingly apparent that women suffer a disproportionate amount of pain
during their lifetime compared to men. Over the past 15 years, a growing number of studies …
during their lifetime compared to men. Over the past 15 years, a growing number of studies …
Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats
Disruption of bacterial colonization during the early postnatal period is increasingly being
linked to adverse health outcomes. Indeed, there is a growing appreciation that the gut …
linked to adverse health outcomes. Indeed, there is a growing appreciation that the gut …
Sex-related hormonal influences on pain and analgesic responses
Considerable evidence indicates sex-related differences in pain responses and in the
effectiveness of various analgesic agents. Specifically, females are at greater risk for …
effectiveness of various analgesic agents. Specifically, females are at greater risk for …
[HTML][HTML] Gender-related differences in irritable bowel syndrome: potential mechanisms of sex hormones
M Meleine, J Matricon - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
According to epidemiological studies, twice as many women as men are affected by irritable
bowel syndrome (IBS) in western countries, suggesting a role for sex hormones in IBS …
bowel syndrome (IBS) in western countries, suggesting a role for sex hormones in IBS …
Gender differences in irritable bowel syndrome
L Chang, MM Heitkemper - Gastroenterology, 2002 - Elsevier
In the United States and other Western cultures, a greater number of women seek health
care services for symptoms of functional pain disorders, including irritable bowel syndrome …
care services for symptoms of functional pain disorders, including irritable bowel syndrome …
Does pain vary across the menstrual cycle? A review
Reproductive hormones are implicated in moderating pain. Animal studies support both
pronociceptive and antinociceptive actions of oestradiol and progesterone suggesting that …
pronociceptive and antinociceptive actions of oestradiol and progesterone suggesting that …
Contribution of GIRK2-mediated postsynaptic signaling to opiate and α2-adrenergic analgesia and analgesic sex differences
I Mitrovic, M Margeta-Mitrovic, S Bader… - Proceedings of the …, 2003 - National Acad Sciences
The analgesia produced by inhibitory G protein-coupled receptor agonists involves
coordinated postsynaptic inhibition via G protein-coupled inwardly rectifying potassium …
coordinated postsynaptic inhibition via G protein-coupled inwardly rectifying potassium …
Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome?
MM Heitkemper, L Chang - Gender medicine, 2009 - Elsevier
Background: An increase in gastrointestinal (GI) symptoms, including bowel discomfort,
abdominal pain/discomfort, bloating, and alterations in bowel patterns, has been reported …
abdominal pain/discomfort, bloating, and alterations in bowel patterns, has been reported …
A life of pelvic pain
KJ Berkley - Physiology & behavior, 2005 - Elsevier
Pelvic pain associated with menstruation, ie, dysmenorrhea, is a chronic pelvic pain that not
only interferes with a woman's wellbeing for a large part of her life but also often co-occurs …
only interferes with a woman's wellbeing for a large part of her life but also often co-occurs …