Tissue engineering has emerged as a new treatment approach for bone repair and
regeneration seeking to address limitations associated with current therapies, such as …

The controlled delivery of growth factors and cells within biomaterial carriers can enhance
and accelerate functional bone formation. The carrier system can be designed with pre …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …

Bone formation is a complex process that requires concerted function of multiple growth
factors. For this, it is essential to design a delivery system with the ability to load multiple …

Successful tissue regeneration strategies focus on the use of novel biomaterials, structures,
and a variety of cues to control cell behavior and promote regeneration. Studies discovered …

Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

Gene therapy involves the introduction of foreign genetic material into cells in order exert a
therapeutic effect. The application of gene therapy to the field of orthopaedic tissue …

A promising strategy to accelerate joint implant integration and reduce recovery time and
failure rates is to deliver a combination of certain growth factors to the integration site. There …