Recent advance in oxazole-based medicinal chemistry
HZ Zhang, ZL Zhao, CH Zhou - European journal of medicinal chemistry, 2018 - Elsevier
Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …
ring are readily able to bind with a variety of enzymes and receptors in biological systems …
A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …
Marine natural products and their synthetic analogs as promising antibiofilm agents for antibiotics discovery and development
Biofilm is a complex microbial consortium that are embedded in a membrane structure of the
extracellular polymeric substances (EPS). As a major form of microorganisms in nature …
extracellular polymeric substances (EPS). As a major form of microorganisms in nature …
Azole and chlorine: An effective combination in battle against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies
Methicillin-resistant Staphylococcus aureus (MRSA) is a threat to human life due to its fast
spread and leading to difficult-to-treat skin and filmsy diseases. The fastest-emerging MRSA …
spread and leading to difficult-to-treat skin and filmsy diseases. The fastest-emerging MRSA …
Biosynthesized silver nanoparticles for inhibition of antibacterial resistance and biofilm formation of methicillin-resistant coagulase negative Staphylococci
The ability of a natural stabilizing and reducing agent on the synthesis of silver nanoparticles
(Ag NPs) was explored using a rapid and single-pot biological reduction method using …
(Ag NPs) was explored using a rapid and single-pot biological reduction method using …
[HTML][HTML] New thiazole nortopsentin analogues inhibit bacterial biofilm formation
A Carbone, B Parrino, MG Cusimano, V Spanò… - Marine drugs, 2018 - mdpi.com
New thiazole nortopsentin analogues were conveniently synthesized and evaluated for their
activity as inhibitors of biofilm formation of relevant Gram-positive and Gram-negative …
activity as inhibitors of biofilm formation of relevant Gram-positive and Gram-negative …
Medicinal purposes: Bioactive metabolites from marine-derived organisms
T Li, T Ding, J Li - Mini reviews in medicinal chemistry, 2019 - ingentaconnect.com
The environment of marine occupies about 95% biosphere of the world and it can be a
critical source of bioactive compounds for humans to be explored. Special environment such …
critical source of bioactive compounds for humans to be explored. Special environment such …
Rapid assembly of pyrrole-ligated 1, 3, 4-oxadiazoles and excellent antibacterial activity of iodophenol substituents
Pyrrole-ligated 1, 3, 4-oxadiazole is a very important pharmacophore which exhibits broad
therapeutic effects such as anti-tuberculosis, anti-epileptic, anti-HIV, anti-cancer, anti …
therapeutic effects such as anti-tuberculosis, anti-epileptic, anti-HIV, anti-cancer, anti …
Synthesis and in vitro evaluation of antibacterial and antibiofilm activities of novel triphenylphosphonium‐functionalized substituted pyrimidines
The increase in the prevalence of antibiotic‐resistant pathogens leads to a decrease in the
number of antimicrobial agents for the treatment of infections and prompts researchers to …
number of antimicrobial agents for the treatment of infections and prompts researchers to …
Antibacterial and antibiofilm activities of synthetic analogs of 3-alkylpyridine marine alkaloids
KMS Herrera, FK da Silva, WG de Lima… - Medicinal Chemistry …, 2020 - Springer
Nowadays, the emergence of superbugs is one of the most serious public health problems.
Strains of Staphylococcus aureus and Klebsiella pneumoniae, resistant to many …
Strains of Staphylococcus aureus and Klebsiella pneumoniae, resistant to many …