The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …

Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

The rapid repurposing of antivirals is particularly pressing during pandemics. However,
rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines …

The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …

Organ-on-A-chip (OoAC) devices are miniaturized, functional, in vitro constructs that aim to
recapitulate the in vivo physiology of an organ using different cell types and extracellular …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

The use of biomaterials for tissue engineering and regenerative medicine applications has
increased dramatically over recent years. However, the clinical uptake of a wide variety of …

In some patients, COVID-19 can trigger neurological symptoms with unclear pathogenesis.
Here we describe a microphysiological system integrating alveolus and blood–brain barrier …

New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

Lung‐on‐a‐chip models hold great promise for disease modeling and drug screening.
Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D …