Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique
biological and physicochemical properties and ability to facilitate biological structure repair …

Hyaluronic acid (HA), one of the main components of the extracellular matrix (ECM), is
extensively used in the design of hydrogels and nanoparticles for different biomedical …

Corneal transplantation remains gold standard for the treatment of severe cornea diseases,
however, scarcity of donor cornea is a serious bottleneck. 3D bioprinting holds tremendous …

Bone marrow stem cells (BMSCs)-loaded injectable hydrogels are promising vehicles for the
restoration of articular cartilage defect (ACD), while was limited with insufficient …

Dysfunction of the central nervous system (CNS) following traumatic brain injuries (TBI),
spinal cord injuries (SCI), or strokes remains challenging to address using existing …

The biomechanical properties of the brain microenvironment, which is composed of different
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …

Methods for studying brain function and disease heavily rely on in vivo animal models, ex-
vivo tissue slices, and 2D cell culture platforms. These methods all have limitations that …

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

In the present study, we report the first synthesis of diazirine-modified hyaluronic acid (HA–
DAZ). In addition, we also produced a precursor polymer solution composed of HA–DAZ and …

Three-dimensional (3D) neuronal cultures are valuable models for studying brain complexity
in vitro, and the choice of the bulk material in which the neurons grow is a crucial factor in …